| SP | Eickhoff, J.Eickhoff, Jerad † >> | 32 | 2015 | R | 100 | 33 | 33 | 18 | 9 | 3.92 | .300 | 1.24 | 8.0 | 3.2 | 10.5 | 227.1 | 203 | 105 | 99 | 29 | 80 | 266 | 1 | 0 | 0 | 1 | 20 | 9 | 1 | 3.49 |
| SP | Arrieta, J.Arrieta, Jake >> | 35 | 2014 | R | 94 | 32 | 32 | 13 | 12 | 4.48 | .311 | 1.30 | 8.1 | 3.7 | 9.4 | 192.2 | 172 | 99 | 96 | 24 | 79 | 201 | 0 | 0 | 0 | 0 | 15 | 10 | 4 | 3.92 |
| SP | Halladay, R.Halladay, Roy † >> | 32 | 2008 | R | 87 | 33 | 32 | 18 | 9 | 3.06 | .278 | 1.13 | 8.2 | 2.0 | 7.5 | 244.0 | 221 | 90 | 83 | 19 | 55 | 203 | 7 | 0 | 0 | 1 | 22 | 6 | 2 | 3.10 |
| RP | Boxberger, B.Boxberger, Brad † >> | 33 | 2014 | R | 96 | 58 | 0 | 6 | 4 | 2.48 | .293 | 1.19 | 6.7 | 4.0 | 12.3 | 58.0 | 43 | 17 | 16 | 4 | 26 | 79 | 0 | 29 | 3 | 0 | 0 | 3 | 1 | 2.67 |
| RP | Bastardo, A.Bastardo, Antonio >> | 30 | 2011 | L | 100 | 94 | 0 | 1 | 3 | 3.31 | .224 | 0.85 | 5.3 | 2.4 | 10.6 | 68.0 | 40 | 25 | 25 | 7 | 18 | 80 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 2.82 |
| RP | Benoit, J.Benoit, Joaquin # >> | 36 | 2010 | R | 96 | 58 | 0 | 0 | 7 | 4.20 | .307 | 1.29 | 8.5 | 3.3 | 9.8 | 55.2 | 52 | 26 | 26 | 12 | 20 | 60 | 0 | 34 | 4 | 0 | 0 | 2 | 0 | 4.85 |
| RP | Dominguez, S.Dominguez, Seranthony >> | 34 | 2018 | R | 92 | 59 | 0 | 3 | 4 | 4.95 | .318 | 1.38 | 7.9 | 4.5 | 9.7 | 40.0 | 35 | 22 | 22 | 7 | 20 | 43 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 4.70 |
| RP | Rivero, F.Rivero, Felipe # >> | 31 | 2015 | L | 91 | 66 | 0 | 1 | 3 | 6.14 | .366 | 1.69 | 12.2 | 3.2 | 12.0 | 51.1 | 69 | 37 | 35 | 9 | 18 | 68 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 3.80 |
| CL | Bailey, A.Bailey, Andrew >> | 27 | 2009 | R | 98 | 92 | 0 | 2 | 4 | 3.86 | .310 | 1.33 | 8.4 | 3.6 | 9.2 | 84.0 | 78 | 37 | 36 | 12 | 34 | 86 | 0 | 2 | 2 | 0 | 0 | 1 | 2 | 4.06 |