| SP | Martinez, P.Martinez, Pedro >> | 34 | 2005 | R | 100 | 23 | 23 | 8 | 10 | 4.52 | .311 | 1.30 | 9.4 | 2.4 | 7.0 | 157.1 | 164 | 79 | 79 | 32 | 41 | 122 | 1 | 0 | 0 | 0 | 11 | 8 | 0 | 5.03 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 94 | 23 | 23 | 10 | 9 | 3.31 | .279 | 1.14 | 8.2 | 2.1 | 7.2 | 177.0 | 161 | 68 | 65 | 24 | 41 | 141 | 7 | 0 | 0 | 0 | 15 | 3 | 4 | 3.92 |
| SP | Eickhoff, J.Eickhoff, Jerad † >> | 34 | 2015 | R | 95 | 23 | 23 | 10 | 7 | 3.68 | .289 | 1.18 | 7.4 | 3.2 | 7.7 | 156.2 | 129 | 65 | 64 | 19 | 56 | 134 | 1 | 0 | 0 | 0 | 14 | 6 | 2 | 4.06 |
| SP | Arrieta, J.Arrieta, Jake >> | 37 | 2014 | R | 89 | 23 | 22 | 9 | 6 | 4.11 | .307 | 1.31 | 8.2 | 3.7 | 8.6 | 129.1 | 117 | 59 | 59 | 15 | 53 | 123 | 0 | 0 | 0 | 0 | 12 | 2 | 6 | 3.88 |
| RP | Bailey, A.Bailey, Andrew >> | 29 | 2009 | R | 99 | 68 | 0 | 0 | 2 | 3.24 | .254 | 1.01 | 7.0 | 2.2 | 9.5 | 66.2 | 51 | 26 | 24 | 9 | 16 | 70 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 3.42 |
| RP | Wagner, B.Wagner, Billy >> | 34 | 2005 | L | 99 | 70 | 0 | 3 | 0 | 1.85 | .240 | 0.90 | 5.6 | 2.6 | 8.6 | 48.2 | 30 | 12 | 10 | 5 | 14 | 46 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 3.44 |
| RP | Benoit, J.Benoit, Joaquin >> | 38 | 2010 | R | 95 | 48 | 0 | 3 | 2 | 2.34 | .246 | 0.92 | 4.8 | 3.7 | 12.7 | 34.2 | 18 | 9 | 9 | 3 | 14 | 48 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 2.74 |
| RP | Boxberger, B.Boxberger, Brad >> | 35 | 2014 | R | 93 | 30 | 0 | 3 | 0 | 0.69 | .250 | 0.96 | 3.8 | 4.8 | 9.7 | 26.0 | 11 | 3 | 2 | 2 | 14 | 28 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.58 |
| RP | Rhodes, A.Rhodes, Arthur >> | 36 | 2005 | L | 91 | 38 | 0 | 2 | 2 | 1.17 | .330 | 1.48 | 8.2 | 5.1 | 8.6 | 23.0 | 21 | 3 | 3 | 0 | 13 | 22 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 2.78 |
| RP | Urbina, U.Urbina, Ugueth >> | 31 | 2005 | R | 90 | 20 | 0 | 2 | 1 | 5.21 | .387 | 1.84 | 9.9 | 6.6 | 10.9 | 19.0 | 21 | 11 | 11 | 1 | 14 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.63 |
| CL | Bastardo, A.Bastardo, Antonio † >> | 32 | 2011 | L | 100 | 52 | 0 | 4 | 5 | 2.75 | .240 | 0.92 | 5.8 | 2.4 | 9.5 | 59.0 | 38 | 21 | 18 | 6 | 16 | 62 | 0 | 30 | 5 | 0 | 0 | 2 | 1 | 3.14 |