| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 98 | 33 | 32 | 6 | 12 | 5.80 | .347 | 1.53 | 9.5 | 4.3 | 7.7 | 132.0 | 139 | 95 | 85 | 19 | 63 | 113 | 0 | 0 | 1 | 0 | 5 | 8 | 5 | 4.77 |
| SP | Price, D.Price, David † >> | 32 | 2012 | L | 92 | 34 | 34 | 15 | 12 | 3.68 | .261 | 1.04 | 7.6 | 1.7 | 8.3 | 242.0 | 205 | 118 | 99 | 35 | 46 | 223 | 4 | 0 | 0 | 1 | 21 | 5 | 5 | 3.67 |
| SP | Porcello, R.Porcello, Rick >> | 36 | 2016 | R | 83 | 34 | 34 | 8 | 14 | 5.04 | .318 | 1.38 | 10.0 | 2.4 | 7.0 | 159.0 | 177 | 97 | 89 | 22 | 42 | 123 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 4.10 |
| SP | Beckett, J.Beckett, Josh >> | 27 | 2007 | R | 80 | 34 | 34 | 10 | 14 | 4.68 | .310 | 1.30 | 8.4 | 3.3 | 7.0 | 171.1 | 159 | 96 | 89 | 29 | 63 | 133 | 0 | 0 | 0 | 0 | 15 | 9 | 4 | 4.91 |
| RP | Jansen, K.Jansen, Kenley >> | 29 | 2012 | R | 100 | 64 | 0 | 4 | 3 | 2.75 | .218 | 0.82 | 4.7 | 2.8 | 9.4 | 75.1 | 39 | 24 | 23 | 6 | 23 | 78 | 0 | 6 | 5 | 0 | 0 | 1 | 2 | 2.92 |
| RP | Delcarmen, M.Delcarmen, Manny >> | 25 | 2007 | R | 93 | 52 | 0 | 4 | 1 | 2.16 | .259 | 0.99 | 6.1 | 2.9 | 9.0 | 66.2 | 45 | 18 | 16 | 6 | 21 | 66 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 3.32 |
| RP | Wheeler, D.Wheeler, Dan # >> | 34 | 2009 | R | 89 | 78 | 0 | 5 | 1 | 3.39 | .245 | 0.97 | 7.0 | 1.8 | 7.7 | 90.1 | 70 | 39 | 34 | 11 | 18 | 77 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.48 |
| RP | Aceves, A.Aceves, Alfredo >> | 29 | 2009 | R | 84 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SU | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 100 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 29 | 2012 | R | 100 | 69 | 0 | 3 | 3 | 2.17 | .251 | 0.97 | 6.0 | 2.8 | 12.8 | 78.2 | 52 | 19 | 19 | 8 | 24 | 111 | 0 | 38 | 2 | 0 | 0 | 3 | 3 | 2.53 |