| SP | Verlander, J.Verlander, Justin >> | 36 | 2011 | R | 100 | 10 | 10 | 7 | 0 | 1.85 | .242 | 0.93 | 5.2 | 3.2 | 6.7 | 73.0 | 42 | 15 | 15 | 5 | 26 | 54 | 1 | 0 | 0 | 1 | 8 | 2 | 2 | 3.56 |
| SP | Clemens, R.Clemens, Roger >> | 45 | 2005 | R | 98 | 10 | 10 | 5 | 1 | 3.86 | .274 | 1.13 | 6.8 | 3.5 | 8.3 | 65.1 | 49 | 28 | 28 | 8 | 25 | 60 | 1 | 0 | 0 | 0 | 7 | 0 | 0 | 3.91 |
| SP | Greinke, Z.Greinke, Zack >> | 44 | 2015 | R | 97 | 10 | 10 | 5 | 3 | 3.88 | .278 | 1.12 | 6.8 | 3.3 | 8.6 | 65.0 | 49 | 30 | 28 | 5 | 24 | 62 | 1 | 0 | 0 | 1 | 5 | 2 | 0 | 3.29 |
| SP | Pettitte, A.Pettitte, Andy >> | 35 | 2005 | L | 91 | 10 | 10 | 3 | 3 | 2.60 | .290 | 1.21 | 8.5 | 2.5 | 5.9 | 72.2 | 68 | 21 | 21 | 6 | 20 | 47 | 1 | 0 | 0 | 0 | 8 | 1 | 1 | 3.65 |
| CL | Osuna, R.Osuna, Roberto >> | 32 | 2015 | R | 98 | 22 | 0 | 2 | 2 | 3.22 | .256 | 1.03 | 7.4 | 2.0 | 12.3 | 22.1 | 18 | 8 | 8 | 2 | 5 | 30 | 0 | 14 | 2 | 0 | 0 | 0 | 0 | 2.14 |
| SU | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 98 | 24 | 0 | 1 | 1 | 5.48 | .310 | 1.30 | 6.7 | 5.1 | 12.1 | 23.0 | 17 | 14 | 14 | 4 | 13 | 31 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 4.39 |
| RP | Gregerson, L.Gregerson, Luke >> | 33 | 2010 | R | 96 | 25 | 0 | 1 | 0 | 1.07 | .224 | 0.83 | 5.4 | 2.2 | 7.2 | 25.1 | 15 | 3 | 3 | 2 | 6 | 20 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.28 |
| RP | Johnson, T.Johnson, Tyler >> | 30 | 2007 | L | 90 | 19 | 0 | 2 | 3 | 3.38 | .238 | 0.88 | 5.1 | 2.8 | 6.2 | 16.0 | 9 | 6 | 6 | 3 | 5 | 11 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.19 |
| RP | Nieve, F.Nieve, Fernando >> | 27 | 2006 | R | 84 | 19 | 0 | 2 | 0 | 0.93 | .194 | 0.67 | 4.7 | 1.4 | 7.6 | 19.1 | 10 | 2 | 2 | 0 | 3 | 16 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1.95 |
| SP | McHugh, C.McHugh, Collin >> | 38 | 2014 | R | 83 | 8 | 0 | 1 | 0 | 1.50 | .289 | 1.17 | 8.5 | 2.0 | 7.5 | 18.0 | 17 | 3 | 3 | 3 | 4 | 15 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.33 |