| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 5 | 5 | 3 | 0 | 2.19 | .240 | 0.89 | 6.6 | 1.5 | 12.6 | 37.0 | 27 | 9 | 9 | 3 | 6 | 52 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 1.89 |
| SP | Rodon, C.Rodon, Carlos # >> | 32 | 2025 | L | 90 | 5 | 5 | 0 | 2 | 6.75 | .345 | 1.58 | 9.4 | 5.0 | 8.6 | 25.1 | 26 | 19 | 19 | 7 | 14 | 24 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 6.40 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 77 | 5 | 5 | 2 | 3 | 5.14 | .288 | 1.21 | 7.4 | 3.5 | 9.3 | 28.0 | 23 | 16 | 16 | 4 | 11 | 29 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 3.96 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 64 | 5 | 5 | 2 | 2 | 4.82 | .328 | 1.39 | 10.3 | 2.3 | 9.3 | 28.0 | 32 | 16 | 15 | 6 | 7 | 29 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.68 |
| RP | Iglesias, R.Iglesias, Raisel >> | 35 | 2025 | R | 80 | 12 | 0 | 1 | 0 | 5.54 | .350 | 1.62 | 10.4 | 4.2 | 13.8 | 13.0 | 15 | 8 | 8 | 4 | 6 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.31 |
| RP | Banks, T.Banks, Tanner >> | 33 | 2025 | L | 71 | 11 | 0 | 1 | 0 | 9.28 | .373 | 1.78 | 11.7 | 5.4 | 5.4 | 10.2 | 13 | 11 | 11 | 5 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.10 |
| RP | Herget, J.Herget, Jimmy >> | 31 | 2025 | R | 53 | 10 | 0 | 0 | 0 | 1.00 | .250 | 1.00 | 7.0 | 2.0 | 4.5 | 18.0 | 14 | 2 | 2 | 1 | 4 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.39 |
| RP | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 90 | 9 | 0 | 0 | 0 | 7.04 | .425 | 2.09 | 11.6 | 9.0 | 6.4 | 7.2 | 9 | 6 | 6 | 0 | 7 | 5 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.00 |
| SU | Keller, B.Keller, Brad >> | 29 | 2025 | R | 91 | 11 | 0 | 1 | 0 | 2.25 | .294 | 1.25 | 9.0 | 2.3 | 13.5 | 12.0 | 12 | 3 | 3 | 1 | 3 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.83 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 100 | 13 | 0 | 0 | 2 | 3.14 | .283 | 1.19 | 7.7 | 3.2 | 9.6 | 14.1 | 12 | 5 | 5 | 1 | 5 | 15 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 2.86 |
| SP | Burrows, M.Burrows, Mike >> | 25 | 2025 | R | 58 | 2 | 0 | 0 | 1 | 20.25 | .556 | 3.75 | 36.0 | 9.0 | 18.0 | 2.2 | 8 | 6 | 6 | 1 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.50 |