| SP | Maddox, N.Maddox, Nick >> | 21 | 1907 | R | 98 | 23 | 23 | 0 | 3 | 2.85 | .289 | 1.20 | 8.0 | 2.9 | 6.0 | 60.0 | 53 | 21 | 19 | 2 | 19 | 40 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.10 |
| SP | Skenes, P.Skenes, Paul † >> | 23 | 2025 | R | 84 | 20 | 20 | 10 | 4 | 2.81 | .265 | 1.07 | 6.9 | 2.7 | 9.6 | 115.1 | 88 | 43 | 36 | 6 | 35 | 123 | 1 | 0 | 0 | 0 | 11 | 2 | 0 | 2.50 |
| RP | Rivero, F.Rivero, Felipe >> | 25 | 2017 | L | 71 | 59 | 0 | 10 | 3 | 3.29 | .274 | 1.09 | 7.0 | 2.7 | 10.0 | 82.0 | 64 | 31 | 30 | 6 | 25 | 91 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 2.79 |
| RP | Rodriguez, R.Rodriguez, Richard >> | 31 | 2021 | R | 69 | 62 | 0 | 4 | 2 | 4.08 | .299 | 1.28 | 9.0 | 2.5 | 6.0 | 75.0 | 75 | 39 | 34 | 10 | 21 | 50 | 0 | 1 | 6 | 0 | 0 | 0 | 5 | 4.24 |
| RP | Melancon, M.Melancon, Mark # >> | 29 | 2014 | R | 63 | 57 | 0 | 3 | 5 | 3.46 | .298 | 1.27 | 9.1 | 2.4 | 7.7 | 67.2 | 68 | 26 | 26 | 7 | 18 | 57 | 0 | 0 | 3 | 0 | 0 | 0 | 4 | 3.46 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 60 | 50 | 0 | 4 | 1 | 3.47 | .295 | 1.24 | 8.7 | 2.6 | 7.9 | 59.2 | 57 | 25 | 23 | 2 | 17 | 52 | 0 | 0 | 3 | 0 | 0 | 1 | 4 | 2.59 |
| RP | Bednar, D.Bednar, David >> | 26 | 2021 | R | 57 | 52 | 0 | 4 | 0 | 1.41 | .239 | 0.93 | 5.9 | 2.6 | 9.9 | 63.2 | 41 | 13 | 10 | 4 | 18 | 69 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 2.54 |
| CL | Borucki, R.Borucki, Ryan † # >> | 29 | 2023 | L | 84 | 50 | 0 | 5 | 4 | 3.51 | .256 | 0.99 | 7.8 | 1.2 | 6.4 | 51.1 | 44 | 23 | 20 | 3 | 7 | 36 | 0 | 26 | 5 | 0 | 0 | 2 | 0 | 2.88 |
| SU | Santana, D.Santana, Dennis >> | 29 | 2025 | R | 70 | 56 | 0 | 2 | 2 | 2.03 | .247 | 0.95 | 5.8 | 2.8 | 6.1 | 62.0 | 40 | 19 | 14 | 4 | 19 | 42 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 3.50 |
| RP | Gossage, R.Gossage, Rich † >> | 26 | 1977 | R | 68 | 52 | 0 | 23 | 1 | 3.33 | .289 | 1.20 | 7.7 | 3.2 | 8.0 | 108.0 | 92 | 45 | 40 | 13 | 38 | 96 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 3.90 |
| SP | Harris, B.Harris, Bill >> | 31 | 1931 | R | 75 | 13 | 2 | 2 | 2 | 4.95 | .326 | 1.45 | 8.6 | 4.5 | 4.5 | 20.0 | 19 | 12 | 11 | 2 | 10 | 10 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.80 |