| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 40 | 40 | 16 | 14 | 3.96 | .311 | 1.33 | 8.8 | 3.3 | 8.9 | 263.2 | 256 | 118 | 116 | 30 | 95 | 261 | 2 | 0 | 0 | 0 | 26 | 6 | 4 | 3.65 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 88 | 38 | 38 | 13 | 16 | 4.40 | .324 | 1.42 | 8.7 | 4.2 | 8.4 | 272.1 | 262 | 139 | 133 | 24 | 126 | 255 | 10 | 0 | 0 | 1 | 20 | 3 | 2 | 3.69 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 79 | 37 | 37 | 14 | 15 | 4.20 | .293 | 1.23 | 8.7 | 2.5 | 5.8 | 248.2 | 239 | 121 | 116 | 32 | 68 | 160 | 5 | 0 | 0 | 1 | 19 | 2 | 9 | 4.23 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 36 | 36 | 16 | 10 | 4.87 | .343 | 1.54 | 9.8 | 4.1 | 7.9 | 212.1 | 231 | 118 | 115 | 21 | 97 | 187 | 0 | 0 | 0 | 0 | 17 | 5 | 4 | 3.97 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 52 | 31 | 31 | 11 | 13 | 4.73 | .313 | 1.35 | 8.4 | 3.8 | 4.8 | 199.2 | 186 | 111 | 105 | 21 | 84 | 107 | 5 | 0 | 0 | 0 | 16 | 3 | 1 | 4.61 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 71 | 0 | 5 | 7 | 1.79 | .207 | 0.76 | 5.9 | 1.0 | 9.6 | 85.2 | 56 | 17 | 17 | 9 | 9 | 91 | 0 | 38 | 4 | 0 | 0 | 2 | 0 | 2.62 |
| SU | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 87 | 62 | 0 | 2 | 5 | 6.53 | .343 | 1.55 | 9.6 | 4.4 | 5.5 | 71.2 | 76 | 52 | 52 | 9 | 35 | 43 | 0 | 5 | 14 | 0 | 0 | 1 | 3 | 4.96 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 73 | 69 | 0 | 5 | 5 | 4.82 | .325 | 1.43 | 9.4 | 3.6 | 8.5 | 74.2 | 77 | 41 | 40 | 7 | 30 | 70 | 0 | 2 | 4 | 0 | 0 | 1 | 3 | 3.59 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 74 | 45 | 0 | 7 | 2 | 2.72 | .284 | 1.19 | 8.0 | 2.7 | 8.0 | 53.0 | 47 | 17 | 16 | 7 | 16 | 47 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.85 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 70 | 23 | 0 | 0 | 1 | 6.26 | .343 | 1.57 | 9.4 | 4.7 | 10.6 | 23.0 | 24 | 16 | 16 | 4 | 12 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.48 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 15 | 0 | 1 | 0 | 8.16 | .394 | 1.95 | 12.2 | 5.8 | 9.0 | 14.1 | 19 | 13 | 13 | 2 | 9 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.79 |
| SP | Martinez, D.Martinez, Dennis >> | 37 | 1992 | R | 53 | 26 | 0 | 1 | 1 | 5.43 | .348 | 1.55 | 10.2 | 3.8 | 4.7 | 116.0 | 131 | 70 | 70 | 10 | 49 | 61 | 0 | 0 | 0 | 0 | 0 | 6 | 1 | 4.49 |