| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 11 | 11 | 6 | 4 | 3.63 | .304 | 1.31 | 8.3 | 3.5 | 8.8 | 79.1 | 73 | 33 | 32 | 8 | 31 | 77 | 1 | 0 | 0 | 0 | 8 | 0 | 0 | 3.54 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 88 | 11 | 11 | 4 | 6 | 4.35 | .324 | 1.42 | 8.5 | 4.4 | 7.7 | 78.2 | 74 | 39 | 38 | 6 | 38 | 67 | 4 | 0 | 0 | 0 | 5 | 1 | 0 | 3.78 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 79 | 11 | 11 | 2 | 8 | 6.48 | .317 | 1.38 | 9.3 | 3.3 | 6.7 | 66.2 | 68 | 49 | 48 | 15 | 24 | 49 | 2 | 0 | 0 | 0 | 3 | 1 | 1 | 5.61 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 11 | 11 | 6 | 3 | 3.24 | .288 | 1.21 | 7.3 | 3.6 | 8.5 | 75.0 | 61 | 27 | 27 | 10 | 30 | 71 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 4.04 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 52 | 10 | 10 | 3 | 4 | 4.57 | .312 | 1.36 | 8.2 | 4.0 | 4.7 | 67.0 | 61 | 38 | 34 | 11 | 30 | 35 | 2 | 0 | 0 | 0 | 5 | 0 | 0 | 5.43 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 14 | 0 | 0 | 0 | 0.00 | .194 | 0.67 | 5.0 | 1.0 | 7.5 | 18.0 | 10 | 0 | 0 | 0 | 2 | 15 | 0 | 7 | 0 | 0 | 0 | 1 | 0 | 1.83 |
| SU | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 87 | 16 | 0 | 1 | 1 | 8.80 | .361 | 1.70 | 11.4 | 4.2 | 6.6 | 15.1 | 19 | 15 | 15 | 3 | 7 | 11 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 5.53 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 73 | 19 | 0 | 0 | 2 | 5.73 | .327 | 1.41 | 9.0 | 3.7 | 7.0 | 22.0 | 22 | 14 | 14 | 3 | 9 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.59 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 74 | 13 | 0 | 2 | 2 | 2.93 | .246 | 0.98 | 7.2 | 1.8 | 8.4 | 15.1 | 12 | 6 | 5 | 2 | 3 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.47 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 70 | 7 | 0 | 0 | 0 | 1.17 | .207 | 0.78 | 6.4 | 1.3 | 11.6 | 7.2 | 5 | 1 | 1 | 0 | 1 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0.86 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 2 | 0 | 0 | 0 | 13.50 | .500 | 3.00 | 18.0 | 18.0 | 9.0 | 1.1 | 2 | 2 | 2 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.00 |
| SP | Martinez, D.Martinez, Dennis >> | 37 | 1992 | R | 53 | 8 | 0 | 0 | 0 | 4.75 | .345 | 1.53 | 10.0 | 3.8 | 6.0 | 36.0 | 40 | 19 | 19 | 2 | 15 | 24 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.81 |