| SP | Martinez, P.Martinez, Pedro † >> | 26 | 1997 | R | 94 | 23 | 23 | 11 | 7 | 2.98 | .283 | 1.19 | 7.2 | 3.5 | 10.4 | 169.1 | 136 | 60 | 56 | 13 | 65 | 195 | 9 | 0 | 0 | 3 | 15 | 0 | 1 | 2.85 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 24 | 2013 | R | 66 | 22 | 22 | 9 | 7 | 4.80 | .321 | 1.41 | 8.4 | 4.3 | 9.0 | 116.1 | 108 | 66 | 62 | 14 | 56 | 116 | 0 | 0 | 0 | 0 | 11 | 1 | 1 | 4.04 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 82 | 22 | 22 | 8 | 7 | 5.55 | .339 | 1.53 | 10.3 | 3.5 | 5.3 | 105.1 | 120 | 69 | 65 | 11 | 41 | 62 | 0 | 0 | 0 | 0 | 6 | 1 | 4 | 4.38 |
| SP | Scherzer, M.Scherzer, Max # >> | 37 | 2021 | R | 96 | 23 | 23 | 6 | 9 | 5.80 | .329 | 1.44 | 9.2 | 3.8 | 8.5 | 108.2 | 110 | 71 | 70 | 9 | 46 | 102 | 1 | 0 | 0 | 1 | 7 | 4 | 0 | 3.58 |
| CL | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 87 | 57 | 0 | 7 | 1 | 3.04 | .276 | 1.13 | 8.4 | 1.8 | 8.2 | 71.0 | 66 | 27 | 24 | 8 | 14 | 65 | 0 | 7 | 2 | 0 | 0 | 1 | 0 | 3.27 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 51 | 0 | 7 | 3 | 3.33 | .283 | 1.19 | 7.8 | 2.8 | 10.2 | 54.0 | 47 | 20 | 20 | 4 | 17 | 61 | 0 | 12 | 3 | 0 | 0 | 0 | 0 | 2.65 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 91 | 51 | 0 | 6 | 2 | 3.52 | .309 | 1.31 | 6.8 | 5.1 | 5.5 | 71.2 | 54 | 35 | 28 | 7 | 40 | 43 | 0 | 2 | 3 | 0 | 0 | 2 | 3 | 4.85 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 82 | 43 | 0 | 1 | 0 | 3.78 | .306 | 1.30 | 6.5 | 5.2 | 9.2 | 50.0 | 36 | 22 | 21 | 5 | 29 | 51 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.06 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 83 | 46 | 0 | 2 | 1 | 4.44 | .331 | 1.44 | 8.0 | 5.2 | 9.3 | 52.2 | 46 | 27 | 26 | 8 | 30 | 54 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 4.77 |
| RP | Hudson, D.Hudson, Daniel # >> | 34 | 2021 | R | 58 | 52 | 0 | 4 | 1 | 5.57 | .317 | 1.39 | 9.5 | 3.2 | 10.6 | 51.2 | 54 | 34 | 32 | 7 | 18 | 60 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.49 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 67 | 43 | 0 | 4 | 0 | 5.44 | .354 | 1.65 | 11.3 | 3.6 | 9.0 | 48.0 | 60 | 30 | 29 | 8 | 19 | 48 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 4.35 |