| SP | Bassitt, C.Bassitt, Chris >> | 32 | 2021 | R | 89 | 25 | 25 | 11 | 10 | 3.84 | .307 | 1.33 | 8.9 | 3.1 | 8.0 | 147.2 | 146 | 75 | 63 | 20 | 50 | 131 | 0 | 0 | 0 | 0 | 13 | 0 | 5 | 4.01 |
| SP | Zito, B.Zito, Barry † # >> | 24 | 2002 | L | 78 | 26 | 26 | 13 | 8 | 3.12 | .251 | 0.98 | 6.4 | 2.5 | 7.2 | 176.0 | 125 | 67 | 61 | 17 | 48 | 140 | 3 | 0 | 0 | 2 | 18 | 4 | 0 | 3.55 |
| SP | Mulder, M.Mulder, Mark # >> | 25 | 2002 | L | 67 | 24 | 24 | 4 | 13 | 5.57 | .342 | 1.54 | 10.1 | 3.8 | 5.9 | 150.1 | 168 | 95 | 93 | 20 | 64 | 98 | 2 | 0 | 0 | 0 | 9 | 2 | 1 | 4.75 |
| SP | Stewart, D.Stewart, Dave >> | 33 | 1990 | R | 65 | 25 | 24 | 6 | 14 | 6.20 | .343 | 1.55 | 10.0 | 4.0 | 5.1 | 152.1 | 169 | 107 | 105 | 26 | 67 | 86 | 4 | 0 | 0 | 1 | 6 | 3 | 3 | 5.47 |
| SP | Montas, F.Montas, Frankie >> | 28 | 2021 | R | 64 | 24 | 22 | 6 | 13 | 4.81 | .334 | 1.48 | 9.0 | 4.3 | 8.2 | 131.0 | 131 | 73 | 70 | 14 | 63 | 120 | 0 | 0 | 0 | 0 | 9 | 3 | 7 | 4.07 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 97 | 68 | 0 | 0 | 6 | 3.77 | .237 | 0.90 | 6.9 | 1.2 | 7.5 | 105.0 | 81 | 46 | 44 | 16 | 14 | 88 | 0 | 3 | 4 | 0 | 0 | 3 | 0 | 3.79 |
| RP | Honeycutt, R.Honeycutt, Rick >> | 36 | 1990 | L | 74 | 57 | 0 | 3 | 1 | 4.07 | .309 | 1.29 | 8.4 | 3.2 | 4.4 | 73.0 | 68 | 35 | 33 | 6 | 26 | 36 | 0 | 3 | 2 | 0 | 0 | 4 | 2 | 4.32 |
| RP | Street, H.Street, Huston >> | 25 | 2008 | R | 62 | 46 | 0 | 2 | 4 | 5.09 | .303 | 1.27 | 7.6 | 3.9 | 7.4 | 58.1 | 49 | 33 | 33 | 9 | 25 | 48 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 4.76 |
| RP | Ziegler, B.Ziegler, Brad >> | 29 | 2008 | R | 61 | 41 | 0 | 3 | 3 | 3.50 | .272 | 1.08 | 6.7 | 3.1 | 4.1 | 46.1 | 34 | 18 | 18 | 2 | 16 | 21 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.83 |
| RP | Trivino, L.Trivino, Lou >> | 29 | 2021 | R | 56 | 23 | 0 | 0 | 0 | 4.39 | .316 | 1.35 | 9.7 | 2.8 | 7.6 | 26.2 | 28 | 14 | 13 | 5 | 8 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 4.85 |