| SP | Wheeler, Z.Wheeler, Zack † >> | 35 | 2025 | R | 98 | 24 | 24 | 12 | 5 | 3.75 | .306 | 1.27 | 8.2 | 3.2 | 9.7 | 153.2 | 140 | 65 | 64 | 19 | 55 | 165 | 0 | 0 | 0 | 0 | 15 | 8 | 3 | 3.69 |
| SP | Sanchez, C.Sanchez, Cristopher >> | 28 | 2025 | L | 80 | 23 | 23 | 9 | 7 | 5.98 | .346 | 1.56 | 11.0 | 3.1 | 10.0 | 128.0 | 156 | 85 | 85 | 32 | 44 | 142 | 0 | 0 | 0 | 0 | 11 | 3 | 3 | 5.13 |
| SP | Luzardo, J.Luzardo, Jesus >> | 27 | 2025 | L | 64 | 23 | 23 | 10 | 8 | 5.11 | .343 | 1.54 | 10.4 | 3.4 | 9.9 | 125.0 | 145 | 75 | 71 | 19 | 47 | 138 | 0 | 0 | 0 | 0 | 8 | 4 | 3 | 3.99 |
| SP | Kershaw, C.Kershaw, Clayton >> | 37 | 2025 | L | 57 | 23 | 23 | 7 | 9 | 5.27 | .334 | 1.45 | 9.3 | 3.8 | 7.7 | 107.2 | 111 | 67 | 63 | 11 | 45 | 91 | 0 | 0 | 0 | 0 | 5 | 6 | 4 | 4.07 |
| CL | Hader, J.Hader, Josh † >> | 31 | 2025 | L | 100 | 48 | 0 | 1 | 5 | 3.81 | .255 | 1.01 | 7.0 | 2.2 | 12.7 | 49.2 | 38 | 22 | 21 | 9 | 12 | 69 | 0 | 29 | 3 | 0 | 0 | 1 | 0 | 3.37 |
| RP | Bednar, D.Bednar, David >> | 30 | 2025 | R | 79 | 61 | 0 | 5 | 2 | 3.26 | .288 | 1.16 | 6.5 | 3.9 | 9.9 | 80.0 | 58 | 30 | 29 | 7 | 35 | 88 | 0 | 2 | 2 | 0 | 0 | 4 | 4 | 3.40 |
| RP | Megill, T.Megill, Trevor >> | 31 | 2025 | R | 70 | 55 | 0 | 3 | 1 | 2.67 | .252 | 0.97 | 5.2 | 3.5 | 10.1 | 67.1 | 39 | 22 | 20 | 4 | 26 | 75 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 2.84 |
| RP | Estrada, J.Estrada, Jeremiah >> | 26 | 2025 | R | 65 | 46 | 0 | 5 | 3 | 1.70 | .260 | 1.00 | 6.1 | 2.9 | 9.7 | 53.0 | 36 | 10 | 10 | 3 | 17 | 57 | 0 | 1 | 2 | 0 | 0 | 3 | 2 | 2.72 |
| RP | Treinen, B.Treinen, Blake >> | 37 | 2025 | R | 11 | 26 | 0 | 2 | 0 | 5.96 | .384 | 1.75 | 10.1 | 6.1 | 10.4 | 25.2 | 28 | 17 | 17 | 2 | 17 | 29 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 4.12 |