| SP | Skubal, T.Skubal, Tarik † $$ >> | 28 | 2025 | L | 100 | 34 | 34 | 23 | 8 | 3.18 | .272 | 1.10 | 7.5 | 2.5 | 10.7 | 243.2 | 202 | 91 | 86 | 23 | 67 | 289 | 6 | 0 | 0 | 4 | 25 | 4 | 2 | 2.73 |
| SP | Horton, C.Horton, Cade >> | 23 | 2025 | R | 77 | 32 | 32 | 11 | 6 | 4.87 | .327 | 1.43 | 10.1 | 2.8 | 7.9 | 170.0 | 190 | 96 | 92 | 24 | 53 | 150 | 0 | 0 | 0 | 0 | 11 | 5 | 1 | 4.09 |
| SP | Kershaw, C.Kershaw, Clayton >> | 37 | 2025 | L | 57 | 32 | 32 | 11 | 8 | 4.75 | .332 | 1.47 | 9.9 | 3.3 | 6.7 | 165.0 | 182 | 91 | 87 | 29 | 60 | 123 | 0 | 0 | 0 | 0 | 8 | 4 | 5 | 4.96 |
| RP | Miller, M.Miller, Mason >> | 26 | 2025 | R | 98 | 83 | 0 | 8 | 3 | 2.04 | .267 | 1.07 | 5.6 | 4.1 | 11.4 | 114.2 | 71 | 30 | 26 | 9 | 52 | 144 | 0 | 2 | 4 | 0 | 0 | 2 | 4 | 2.92 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 88 | 85 | 0 | 7 | 6 | 4.88 | .353 | 1.61 | 9.1 | 5.4 | 10.2 | 107.0 | 108 | 62 | 58 | 17 | 64 | 121 | 0 | 6 | 6 | 0 | 0 | 3 | 0 | 4.68 |
| RP | Whitlock, G.Whitlock, Garrett >> | 29 | 2025 | R | 75 | 59 | 0 | 2 | 2 | 4.52 | .340 | 1.52 | 10.1 | 3.7 | 11.0 | 73.2 | 82 | 38 | 37 | 13 | 30 | 89 | 0 | 9 | 4 | 0 | 0 | 2 | 3 | 4.19 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 90 | 45 | 0 | 5 | 2 | 2.43 | .261 | 1.02 | 7.2 | 2.1 | 9.2 | 55.2 | 44 | 15 | 15 | 4 | 13 | 56 | 0 | 4 | 0 | 0 | 0 | 2 | 1 | 2.73 |
| RP | Munoz, A.Munoz, Andres >> | 26 | 2025 | R | 90 | 44 | 0 | 3 | 2 | 2.93 | .281 | 1.14 | 6.1 | 4.3 | 9.8 | 55.1 | 37 | 20 | 18 | 4 | 26 | 60 | 0 | 2 | 1 | 0 | 0 | 2 | 6 | 3.29 |