| SP | Buchholz, C.Buchholz, Clay >> | 34 | 2018 | R | 52 | 9 | 9 | 2 | 6 | 5.68 | .359 | 1.66 | 11.1 | 4.0 | 5.4 | 52.1 | 64 | 38 | 33 | 7 | 23 | 31 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 4.94 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 50 | 9 | 9 | 2 | 3 | 4.98 | .323 | 1.41 | 9.6 | 3.1 | 6.3 | 43.1 | 46 | 24 | 24 | 6 | 15 | 30 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 4.53 |
| SP | Kelly, M.Kelly, Merrill # >> | 33 | 2022 | R | 47 | 9 | 9 | 1 | 5 | 5.23 | .295 | 1.24 | 8.6 | 2.6 | 5.5 | 51.2 | 49 | 31 | 30 | 8 | 15 | 31 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 4.76 |
| SP | Johnson, R.Johnson, Randy >> | 45 | 2008 | L | 34 | 9 | 9 | 1 | 6 | 7.31 | .379 | 1.83 | 13.1 | 3.5 | 5.3 | 44.1 | 64 | 37 | 36 | 10 | 17 | 26 | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 5.93 |
| RP | Kim, B.Kim, Byung-Hyun >> | 22 | 2001 | R | 55 | 28 | 0 | 2 | 3 | 2.70 | .289 | 1.22 | 5.5 | 5.7 | 6.8 | 46.2 | 28 | 15 | 14 | 1 | 29 | 35 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 3.65 |
| RP | Ziegler, B.Ziegler, Brad >> | 36 | 2015 | R | 48 | 26 | 0 | 2 | 0 | 4.19 | .261 | 1.01 | 7.1 | 2.1 | 6.4 | 38.2 | 30 | 18 | 18 | 7 | 9 | 27 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 4.84 |
| RP | Bradley, A.Bradley, Archie >> | 24 | 2017 | R | 43 | 28 | 0 | 0 | 2 | 2.06 | .255 | 1.03 | 6.4 | 2.8 | 11.1 | 35.0 | 25 | 9 | 8 | 3 | 11 | 43 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Valverde, J.Valverde, Jose >> | 28 | 2007 | R | 40 | 21 | 0 | 1 | 1 | 2.52 | .257 | 1.04 | 6.2 | 3.3 | 9.8 | 35.2 | 24 | 10 | 10 | 2 | 13 | 38 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.69 |
| RP | Villarreal, O.Villarreal, Oscar >> | 22 | 2003 | R | 22 | 13 | 0 | 0 | 1 | 5.40 | .286 | 1.20 | 7.2 | 3.6 | 5.9 | 20.0 | 16 | 12 | 12 | 3 | 8 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.85 |