| SP | Skubal, T.Skubal, Tarik # >> | 28 | 2025 | L | 88 | 26 | 26 | 11 | 4 | 4.03 | .291 | 1.22 | 8.4 | 2.7 | 9.1 | 158.2 | 147 | 75 | 71 | 18 | 47 | 159 | 2 | 0 | 0 | 1 | 15 | 1 | 3 | 3.38 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 75 | 25 | 25 | 8 | 5 | 4.68 | .291 | 1.21 | 8.5 | 2.5 | 9.1 | 132.2 | 124 | 71 | 69 | 25 | 36 | 133 | 1 | 0 | 0 | 0 | 15 | 3 | 2 | 4.33 |
| SP | Melton, T.Melton, Troy >> | 24 | 2025 | R | 73 | 25 | 25 | 0 | 4 | 4.60 | .352 | 1.60 | 9.5 | 5.0 | 5.0 | 72.1 | 76 | 42 | 37 | 13 | 40 | 40 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 5.99 |
| SP | Lolich, M.Lolich, Mickey >> | 28 | 1968 | L | 40 | 24 | 24 | 7 | 9 | 6.02 | .326 | 1.42 | 9.1 | 3.8 | 6.9 | 116.2 | 117 | 82 | 78 | 13 | 49 | 89 | 0 | 0 | 0 | 0 | 8 | 3 | 3 | 4.27 |
| SP | Olson, R.Olson, Reese # >> | 23 | 2023 | R | 39 | 23 | 23 | 9 | 5 | 5.84 | .332 | 1.48 | 9.7 | 3.7 | 6.8 | 98.2 | 106 | 72 | 64 | 24 | 40 | 74 | 0 | 0 | 0 | 0 | 6 | 1 | 3 | 5.93 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 88 | 64 | 0 | 5 | 3 | 3.04 | .293 | 1.22 | 7.3 | 3.8 | 8.3 | 91.2 | 74 | 34 | 31 | 9 | 38 | 84 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 3.76 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 72 | 64 | 0 | 11 | 3 | 3.32 | .289 | 1.21 | 7.1 | 3.9 | 6.1 | 116.2 | 91 | 46 | 43 | 16 | 50 | 79 | 0 | 4 | 2 | 0 | 0 | 1 | 7 | 4.75 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 62 | 65 | 0 | 4 | 10 | 5.03 | .315 | 1.37 | 9.0 | 3.4 | 6.9 | 118.0 | 118 | 69 | 66 | 18 | 44 | 90 | 0 | 10 | 6 | 0 | 0 | 1 | 0 | 4.60 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 78 | 51 | 0 | 2 | 4 | 4.88 | .352 | 1.58 | 9.8 | 4.4 | 10.1 | 59.0 | 64 | 33 | 32 | 14 | 29 | 66 | 0 | 2 | 4 | 0 | 0 | 3 | 1 | 5.47 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 67 | 45 | 0 | 4 | 6 | 5.58 | .330 | 1.46 | 9.2 | 4.0 | 8.5 | 50.0 | 51 | 33 | 31 | 11 | 22 | 47 | 0 | 4 | 1 | 0 | 0 | 1 | 3 | 5.36 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 49 | 45 | 0 | 4 | 1 | 1.72 | .245 | 0.94 | 4.4 | 4.1 | 6.2 | 57.2 | 28 | 11 | 11 | 4 | 26 | 39 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 4.02 |