| SP | Bender, C.Bender, Chief >> | 20 | 1904 | R | 38 | 26 | 26 | 12 | 8 | 4.10 | .320 | 1.41 | 9.2 | 3.5 | 6.0 | 197.1 | 202 | 100 | 90 | 21 | 76 | 132 | 5 | 0 | 0 | 0 | 14 | 1 | 7 | 4.22 |
| SP | Bosman, D.Bosman, Dick >> | 31 | 1975 | R | 30 | 25 | 25 | 4 | 14 | 6.21 | .352 | 1.61 | 11.4 | 3.2 | 4.4 | 153.2 | 193 | 112 | 106 | 20 | 54 | 74 | 1 | 0 | 0 | 1 | 10 | 3 | 1 | 4.85 |
| SP | Kazmir, S.Kazmir, Scott >> | 30 | 2014 | L | 31 | 24 | 24 | 8 | 11 | 5.70 | .336 | 1.51 | 10.7 | 2.9 | 6.6 | 158.0 | 188 | 109 | 100 | 34 | 51 | 115 | 2 | 0 | 0 | 0 | 7 | 1 | 8 | 5.33 |
| SP | Krausse, L.Krausse, Lew >> | 25 | 1968 | R | 33 | 24 | 24 | 10 | 10 | 4.81 | .340 | 1.52 | 9.3 | 4.4 | 5.6 | 144.0 | 148 | 80 | 77 | 18 | 71 | 90 | 0 | 0 | 0 | 0 | 10 | 4 | 1 | 4.94 |
| SP | Moscoso, G.Moscoso, Guillermo >> | 27 | 2011 | R | 42 | 24 | 24 | 9 | 7 | 5.60 | .344 | 1.57 | 10.3 | 3.9 | 5.6 | 149.1 | 170 | 107 | 93 | 25 | 64 | 92 | 0 | 0 | 0 | 0 | 11 | 1 | 0 | 5.26 |
| CL | Street, H.Street, Huston >> | 24 | 2007 | R | 61 | 46 | 0 | 3 | 5 | 5.56 | .317 | 1.39 | 9.2 | 3.4 | 10.6 | 45.1 | 46 | 32 | 28 | 9 | 17 | 53 | 0 | 23 | 4 | 0 | 0 | 0 | 0 | 4.38 |
| SU | Petit, Y.Petit, Yusmeiro >> | 37 | 2021 | R | 34 | 36 | 0 | 0 | 0 | 2.68 | .293 | 1.22 | 7.5 | 3.4 | 5.4 | 37.0 | 31 | 11 | 11 | 3 | 14 | 22 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 4.08 |
| RP | Knowles, D.Knowles, Darold >> | 30 | 1971 | L | 38 | 65 | 0 | 3 | 0 | 4.32 | .310 | 1.35 | 8.8 | 3.4 | 5.9 | 75.0 | 73 | 37 | 36 | 8 | 28 | 49 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.20 |
| RP | Blevins, J.Blevins, Jerry # >> | 30 | 2013 | L | 40 | 50 | 0 | 6 | 1 | 3.71 | .283 | 1.18 | 7.8 | 2.9 | 5.1 | 53.1 | 46 | 22 | 22 | 9 | 17 | 30 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.04 |
| RP | Calero, K.Calero, Kiko >> | 30 | 2005 | R | 37 | 30 | 0 | 3 | 1 | 4.91 | .256 | 1.03 | 7.1 | 2.2 | 8.2 | 33.0 | 26 | 19 | 18 | 7 | 8 | 30 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 4.67 |
| RP | Doolittle, S.Doolittle, Sean >> | 29 | 2016 | L | 44 | 19 | 0 | 3 | 1 | 5.09 | .317 | 1.39 | 10.6 | 2.0 | 8.2 | 23.0 | 27 | 13 | 13 | 5 | 5 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.65 |
| RP | Mathews, T.Mathews, T.J. >> | 29 | 1999 | R | 36 | 20 | 0 | 2 | 1 | 5.48 | .312 | 1.27 | 9.0 | 2.6 | 6.4 | 21.1 | 21 | 14 | 13 | 4 | 6 | 15 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.19 |
| RP | Scribner, E.Scribner, Evan >> | 29 | 2015 | R | 39 | 22 | 0 | 1 | 0 | 5.20 | .303 | 1.30 | 10.7 | 1.3 | 9.0 | 27.2 | 32 | 16 | 16 | 3 | 4 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.89 |