| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 86 | 10 | 10 | 4 | 3 | 4.45 | .282 | 1.15 | 8.7 | 1.7 | 8.7 | 62.2 | 60 | 33 | 31 | 10 | 12 | 60 | 2 | 0 | 0 | 1 | 4 | 2 | 0 | 3.84 |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 92 | 10 | 10 | 6 | 1 | 3.39 | .271 | 1.12 | 8.1 | 2.0 | 7.7 | 63.2 | 57 | 24 | 24 | 7 | 14 | 54 | 1 | 0 | 0 | 1 | 7 | 0 | 1 | 3.40 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 79 | 10 | 10 | 4 | 4 | 4.15 | .299 | 1.26 | 8.9 | 2.5 | 8.7 | 65.0 | 64 | 32 | 30 | 11 | 18 | 63 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 4.14 |
| SP | Lolich, M.Lolich, Mickey # >> | 28 | 1968 | L | 46 | 10 | 10 | 1 | 2 | 7.02 | .414 | 2.05 | 14.0 | 4.4 | 7.7 | 41.0 | 64 | 34 | 32 | 8 | 20 | 35 | 0 | 0 | 0 | 0 | 1 | 3 | 1 | 5.51 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 89 | 29 | 0 | 5 | 0 | 3.00 | .236 | 0.90 | 5.4 | 2.8 | 8.4 | 42.0 | 25 | 14 | 14 | 3 | 13 | 39 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.07 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 62 | 26 | 0 | 7 | 1 | 3.38 | .287 | 1.21 | 9.2 | 1.7 | 6.4 | 48.0 | 49 | 19 | 18 | 3 | 9 | 34 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 2.96 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 67 | 20 | 0 | 0 | 1 | 2.18 | .272 | 1.12 | 7.6 | 2.5 | 8.2 | 33.0 | 28 | 9 | 8 | 0 | 9 | 30 | 0 | 6 | 1 | 0 | 0 | 0 | 1 | 2.00 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 50 | 13 | 0 | 3 | 0 | 1.06 | .239 | 0.94 | 3.2 | 5.3 | 6.4 | 17.0 | 6 | 2 | 2 | 1 | 10 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.12 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 79 | 9 | 0 | 0 | 1 | 6.48 | .306 | 1.32 | 7.9 | 4.5 | 9.0 | 8.1 | 7 | 6 | 6 | 1 | 4 | 8 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 4.13 |
| RP | Lasher, F.Lasher, Fred >> | 26 | 1967 | R | 29 | 10 | 0 | 1 | 1 | 5.65 | .295 | 1.26 | 10.3 | 1.3 | 4.5 | 14.1 | 16 | 9 | 9 | 3 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.21 |