| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 87 | 25 | 25 | 6 | 13 | 4.85 | .319 | 1.38 | 9.4 | 3.0 | 9.1 | 167.0 | 175 | 93 | 90 | 22 | 56 | 168 | 1 | 0 | 0 | 0 | 11 | 4 | 3 | 3.78 |
| SP | Greinke, Z.Greinke, Zack † # >> | 36 | 2019 | R | 74 | 24 | 24 | 16 | 5 | 2.96 | .246 | 0.98 | 7.5 | 1.4 | 6.2 | 182.2 | 151 | 61 | 60 | 18 | 28 | 125 | 2 | 0 | 0 | 2 | 17 | 0 | 0 | 3.37 |
| SP | Kelly, M.Kelly, Merrill # >> | 31 | 2020 | R | 54 | 24 | 24 | 0 | 7 | 6.67 | .339 | 1.52 | 10.6 | 3.1 | 5.9 | 55.1 | 65 | 41 | 41 | 16 | 19 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.56 |
| RP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 77 | 70 | 0 | 7 | 6 | 4.07 | .280 | 1.15 | 7.3 | 3.0 | 7.1 | 128.1 | 104 | 58 | 58 | 14 | 43 | 101 | 0 | 11 | 3 | 0 | 0 | 3 | 3 | 3.92 |
| RP | Ramirez, N.Ramirez, Noe >> | 31 | 2021 | R | 76 | 59 | 0 | 2 | 3 | 3.72 | .302 | 1.30 | 7.7 | 4.2 | 5.4 | 67.2 | 57 | 33 | 28 | 6 | 31 | 40 | 0 | 7 | 2 | 0 | 0 | 0 | 4 | 4.36 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 74 | 40 | 0 | 5 | 4 | 3.68 | .303 | 1.27 | 6.9 | 4.6 | 9.9 | 51.1 | 39 | 21 | 21 | 5 | 26 | 56 | 0 | 3 | 2 | 0 | 0 | 2 | 3 | 3.73 |
| RP | Ginkel, K.Ginkel, Kevin >> | 29 | 2023 | R | 59 | 27 | 0 | 0 | 3 | 5.52 | .316 | 1.35 | 7.3 | 4.9 | 10.2 | 31.0 | 25 | 19 | 19 | 4 | 17 | 35 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 4.16 |
| RP | Medders, B.Medders, Brandon >> | 25 | 2005 | R | 47 | 19 | 0 | 2 | 2 | 5.40 | .333 | 1.45 | 8.6 | 4.5 | 7.2 | 20.0 | 19 | 12 | 12 | 5 | 10 | 16 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 6.30 |
| RP | Garcia, R.Garcia, Robert >> | 28 | 2024 | L | 32 | 14 | 0 | 0 | 0 | 5.74 | .254 | 1.02 | 8.4 | 1.2 | 10.2 | 15.2 | 14 | 11 | 10 | 4 | 2 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.60 |
| RP | Gilbert, T.Gilbert, Tyler >> | 28 | 2022 | L | 18 | 19 | 0 | 0 | 1 | 4.45 | .302 | 1.27 | 8.4 | 3.1 | 5.3 | 32.1 | 30 | 16 | 16 | 5 | 11 | 19 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.97 |
| SP | Smith, C.Smith, Charlie >> | 28 | 1908 | R | 24 | 4 | 2 | 1 | 1 | 4.71 | .284 | 1.14 | 7.3 | 3.0 | 3.4 | 21.0 | 17 | 11 | 11 | 5 | 7 | 8 | 1 | 1 | 0 | 0 | 2 | 1 | 0 | 6.48 |