| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 21 | 21 | 10 | 8 | 4.36 | .330 | 1.45 | 8.7 | 4.4 | 5.3 | 130.0 | 125 | 69 | 63 | 17 | 64 | 77 | 1 | 0 | 0 | 0 | 10 | 3 | 1 | 5.06 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 21 | 21 | 5 | 14 | 7.17 | .393 | 1.92 | 12.6 | 4.7 | 5.4 | 116.2 | 163 | 97 | 93 | 24 | 61 | 69 | 0 | 0 | 0 | 0 | 5 | 3 | 0 | 6.16 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 22 | 21 | 8 | 10 | 6.20 | .342 | 1.54 | 10.9 | 3.0 | 5.0 | 127.2 | 154 | 93 | 88 | 31 | 43 | 71 | 3 | 0 | 0 | 0 | 6 | 2 | 3 | 6.12 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 21 | 20 | 6 | 10 | 5.18 | .340 | 1.52 | 11.3 | 2.5 | 6.5 | 128.2 | 161 | 79 | 74 | 16 | 35 | 92 | 3 | 0 | 0 | 0 | 9 | 3 | 1 | 4.08 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 93 | 40 | 0 | 4 | 1 | 2.56 | .286 | 1.20 | 6.2 | 4.8 | 10.8 | 45.2 | 31 | 13 | 13 | 5 | 24 | 54 | 0 | 24 | 1 | 0 | 0 | 0 | 0 | 3.64 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 55 | 0 | 1 | 4 | 5.24 | .335 | 1.49 | 9.5 | 3.9 | 10.5 | 55.0 | 58 | 33 | 32 | 12 | 24 | 64 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.87 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 41 | 0 | 2 | 1 | 4.37 | .346 | 1.54 | 9.4 | 4.6 | 9.4 | 45.1 | 47 | 23 | 22 | 5 | 23 | 47 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 4.02 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 30 | 0 | 1 | 0 | 3.69 | .299 | 1.28 | 8.5 | 3.0 | 6.7 | 39.0 | 37 | 17 | 16 | 6 | 13 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.51 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 24 | 0 | 0 | 0 | 3.41 | .285 | 1.19 | 7.4 | 3.4 | 5.3 | 34.1 | 28 | 13 | 13 | 4 | 13 | 20 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.50 |