| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 22 | 22 | 8 | 10 | 3.53 | .312 | 1.33 | 8.1 | 4.0 | 8.0 | 147.2 | 132 | 68 | 58 | 15 | 65 | 131 | 0 | 0 | 0 | 0 | 14 | 4 | 4 | 3.95 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 83 | 21 | 21 | 12 | 4 | 3.86 | .275 | 1.13 | 8.1 | 2.1 | 4.2 | 163.1 | 146 | 70 | 70 | 22 | 38 | 76 | 2 | 0 | 0 | 1 | 11 | 2 | 1 | 4.56 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 21 | 21 | 7 | 11 | 4.87 | .339 | 1.50 | 9.2 | 4.3 | 5.8 | 146.0 | 150 | 83 | 79 | 16 | 69 | 94 | 2 | 0 | 0 | 0 | 11 | 6 | 3 | 4.68 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 20 | 20 | 7 | 9 | 4.37 | .304 | 1.27 | 8.5 | 2.9 | 4.2 | 156.2 | 148 | 85 | 76 | 14 | 51 | 73 | 8 | 0 | 0 | 0 | 9 | 6 | 2 | 4.33 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 47 | 0 | 1 | 0 | 4.54 | .335 | 1.51 | 5.6 | 8.3 | 7.5 | 37.2 | 23 | 20 | 19 | 5 | 34 | 31 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.84 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 80 | 34 | 0 | 3 | 2 | 1.50 | .244 | 0.97 | 6.0 | 2.7 | 9.6 | 30.0 | 20 | 7 | 5 | 1 | 9 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 2.20 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 17 | 0 | 1 | 0 | 0.00 | .224 | 0.87 | 3.6 | 4.2 | 9.0 | 15.0 | 6 | 0 | 0 | 0 | 7 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 2.40 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 55 | 1 | 0 | 0 | 0 | 8.10 | .444 | 2.10 | 15.0 | 6.0 | 9.0 | 3.1 | 5 | 3 | 3 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.00 |