| SP | Koufax, S.Koufax, Sandy † # >> | 30 | 1965 | L | 97 | 22 | 22 | 11 | 10 | 3.46 | .258 | 1.03 | 7.4 | 1.9 | 7.9 | 176.2 | 145 | 71 | 68 | 19 | 37 | 155 | 11 | 0 | 0 | 0 | 11 | 2 | 3 | 3.31 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 21 | 21 | 6 | 8 | 5.47 | .331 | 1.45 | 9.8 | 3.3 | 7.1 | 130.0 | 142 | 85 | 79 | 17 | 47 | 103 | 3 | 0 | 0 | 1 | 7 | 4 | 2 | 4.29 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 21 | 21 | 11 | 6 | 4.50 | .308 | 1.30 | 8.9 | 2.8 | 3.6 | 144.0 | 142 | 73 | 72 | 18 | 45 | 58 | 5 | 0 | 0 | 2 | 8 | 5 | 6 | 4.86 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 21 | 21 | 9 | 7 | 4.65 | .317 | 1.37 | 9.6 | 2.8 | 4.5 | 153.0 | 163 | 85 | 79 | 19 | 47 | 76 | 6 | 0 | 0 | 0 | 11 | 3 | 2 | 4.60 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 23 | 21 | 10 | 4 | 4.95 | .313 | 1.36 | 8.9 | 3.3 | 5.7 | 156.1 | 155 | 91 | 86 | 25 | 57 | 99 | 5 | 0 | 0 | 0 | 7 | 2 | 1 | 4.95 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 53 | 0 | 10 | 3 | 2.84 | .265 | 1.07 | 6.3 | 3.4 | 10.4 | 66.2 | 46 | 24 | 21 | 2 | 25 | 76 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 2.27 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 40 | 0 | 2 | 2 | 3.50 | .298 | 1.25 | 7.8 | 3.5 | 8.8 | 46.1 | 40 | 19 | 18 | 2 | 18 | 45 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 2.85 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 29 | 0 | 4 | 2 | 1.36 | .277 | 1.15 | 4.6 | 5.7 | 10.4 | 33.0 | 17 | 5 | 5 | 1 | 21 | 38 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 3.00 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 16 | 0 | 0 | 0 | 2.40 | .357 | 1.67 | 8.4 | 6.6 | 9.6 | 15.0 | 14 | 5 | 4 | 2 | 11 | 16 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.80 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 8 | 0 | 1 | 0 | 2.25 | .226 | 0.88 | 5.6 | 2.3 | 13.5 | 8.0 | 5 | 3 | 2 | 1 | 2 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.38 |