| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 92 | 11 | 11 | 5 | 3 | 3.38 | .290 | 1.17 | 7.4 | 3.1 | 9.7 | 69.1 | 57 | 27 | 26 | 11 | 24 | 74 | 0 | 0 | 0 | 0 | 10 | 4 | 0 | 4.14 |
| SP | Flaherty, J.Flaherty, Jack >> | 28 | 2024 | R | 79 | 11 | 11 | 3 | 1 | 5.17 | .350 | 1.57 | 10.4 | 3.8 | 7.8 | 38.1 | 44 | 23 | 22 | 5 | 16 | 33 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4.39 |
| SP | Melton, T.Melton, Troy # >> | 24 | 2025 | R | 73 | 11 | 11 | 0 | 3 | 6.68 | .374 | 1.70 | 11.3 | 4.2 | 7.0 | 32.1 | 40 | 25 | 24 | 7 | 15 | 25 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.97 |
| SP | Lolich, M.Lolich, Mickey >> | 28 | 1968 | L | 42 | 11 | 11 | 3 | 1 | 3.93 | .311 | 1.31 | 8.5 | 3.4 | 5.9 | 50.1 | 47 | 22 | 22 | 7 | 19 | 33 | 0 | 0 | 0 | 0 | 2 | 2 | 1 | 4.76 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 84 | 32 | 0 | 7 | 0 | 3.27 | .311 | 1.31 | 8.3 | 3.5 | 8.3 | 41.1 | 38 | 16 | 15 | 4 | 16 | 38 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 3.73 |
| RP | McMahon, D.McMahon, Don >> | 38 | 1968 | R | 65 | 33 | 0 | 3 | 3 | 2.74 | .324 | 1.38 | 8.3 | 4.2 | 6.1 | 49.1 | 45 | 17 | 15 | 2 | 23 | 33 | 0 | 1 | 0 | 0 | 0 | 3 | 3 | 3.78 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 61 | 37 | 0 | 4 | 2 | 3.35 | .271 | 1.08 | 7.8 | 1.9 | 7.8 | 51.0 | 44 | 20 | 19 | 6 | 11 | 44 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.57 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 78 | 30 | 0 | 3 | 2 | 1.82 | .294 | 1.15 | 6.8 | 3.7 | 10.6 | 29.2 | 22 | 10 | 6 | 4 | 12 | 34 | 0 | 2 | 1 | 0 | 0 | 3 | 1 | 4.00 |
| RP | Rondon, B.Rondon, Bruce >> | 25 | 2016 | R | 63 | 37 | 0 | 1 | 3 | 3.45 | .282 | 1.15 | 7.0 | 3.5 | 9.3 | 31.1 | 24 | 14 | 12 | 3 | 12 | 32 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 3.45 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 56 | 29 | 0 | 2 | 0 | 2.60 | .278 | 1.13 | 6.9 | 3.4 | 5.3 | 34.2 | 26 | 10 | 10 | 0 | 13 | 20 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 3.06 |