| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 81 | 13 | 10 | 4 | 6 | 3.77 | .304 | 1.28 | 9.6 | 2.0 | 9.3 | 71.2 | 76 | 39 | 30 | 12 | 16 | 73 | 0 | 1 | 0 | 0 | 6 | 2 | 1 | 3.90 |
| SP | Pivetta, N.Pivetta, Nick # >> | 32 | 2025 | R | 80 | 13 | 10 | 7 | 3 | 4.75 | .341 | 1.51 | 9.8 | 3.8 | 7.4 | 66.1 | 72 | 38 | 35 | 9 | 28 | 54 | 0 | 0 | 1 | 0 | 5 | 3 | 0 | 4.55 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 70 | 10 | 8 | 4 | 4 | 3.36 | .312 | 1.31 | 6.9 | 5.0 | 7.8 | 61.2 | 47 | 24 | 23 | 3 | 34 | 53 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 3.72 |
| SP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 100 | 11 | 11 | 0 | 0 | 2.48 | .252 | 1.01 | 5.3 | 3.9 | 9.6 | 32.2 | 19 | 9 | 9 | 4 | 14 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.81 |
| SP | Paddack, C.Paddack, Chris >> | 23 | 2019 | R | 71 | 11 | 11 | 4 | 4 | 4.55 | .338 | 1.53 | 11.1 | 2.7 | 8.8 | 59.1 | 73 | 31 | 30 | 8 | 18 | 58 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 3.71 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 99 | 36 | 0 | 2 | 0 | 3.96 | .306 | 1.29 | 8.3 | 3.5 | 10.0 | 36.1 | 33 | 17 | 16 | 2 | 14 | 40 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 2.75 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 95 | 33 | 0 | 3 | 2 | 2.06 | .244 | 0.94 | 5.1 | 3.5 | 8.1 | 39.1 | 22 | 11 | 9 | 2 | 15 | 35 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 3.10 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 89 | 20 | 0 | 1 | 1 | 2.70 | .298 | 1.20 | 8.0 | 3.1 | 7.6 | 26.2 | 23 | 8 | 8 | 1 | 9 | 22 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 3.08 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 80 | 34 | 0 | 2 | 0 | 2.90 | .285 | 1.19 | 6.1 | 4.6 | 8.1 | 31.0 | 21 | 13 | 10 | 1 | 16 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.16 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 74 | 34 | 0 | 2 | 0 | 2.73 | .326 | 1.42 | 8.1 | 5.0 | 7.1 | 29.2 | 26 | 11 | 9 | 0 | 16 | 23 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 3.17 |
| SP | Luebke, C.Luebke, Cory >> | 26 | 2011 | L | 60 | 9 | 5 | 0 | 4 | 7.88 | .422 | 2.19 | 15.8 | 3.9 | 8.4 | 16.0 | 28 | 24 | 14 | 5 | 7 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 6.50 |