| SP | Springs, J.Springs, Jeffrey >> | 29 | 2022 | L | 48 | 11 | 11 | 2 | 4 | 5.40 | .340 | 1.52 | 10.0 | 3.8 | 8.6 | 43.1 | 48 | 27 | 26 | 7 | 18 | 41 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.53 |
| SP | Odorizzi, J.Odorizzi, Jake >> | 25 | 2015 | R | 39 | 11 | 11 | 1 | 7 | 5.40 | .353 | 1.62 | 10.5 | 4.2 | 4.5 | 66.2 | 77 | 41 | 40 | 9 | 31 | 33 | 0 | 0 | 0 | 0 | 6 | 1 | 0 | 5.23 |
| SP | Garza, M.Garza, Matt # >> | 26 | 2009 | R | 35 | 12 | 12 | 0 | 8 | 7.38 | .364 | 1.70 | 12.1 | 3.4 | 6.0 | 64.2 | 86 | 55 | 53 | 15 | 24 | 43 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 5.88 |
| SP | Kazmir, S.Kazmir, Scott >> | 21 | 2005 | L | 25 | 11 | 11 | 4 | 4 | 5.34 | .348 | 1.60 | 9.2 | 5.4 | 7.4 | 57.1 | 58 | 35 | 34 | 4 | 34 | 47 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 4.05 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 88 | 35 | 0 | 0 | 2 | 3.15 | .267 | 1.05 | 5.6 | 4.0 | 9.0 | 45.2 | 28 | 18 | 16 | 2 | 20 | 45 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 3.04 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 87 | 33 | 0 | 3 | 3 | 3.92 | .295 | 1.21 | 7.7 | 3.3 | 8.6 | 41.1 | 35 | 19 | 18 | 5 | 15 | 39 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 3.93 |
| RP | Hernandez, R.Hernandez, Roberto >> | 35 | 1999 | R | 14 | 19 | 0 | 0 | 0 | 7.13 | .374 | 1.71 | 11.6 | 3.8 | 6.4 | 24.0 | 31 | 23 | 19 | 3 | 10 | 17 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.71 |