| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 100 | 27 | 27 | 10 | 7 | 3.18 | .278 | 1.16 | 7.8 | 2.6 | 8.7 | 175.1 | 152 | 70 | 62 | 11 | 51 | 169 | 0 | 0 | 0 | 0 | 18 | 0 | 0 | 2.76 |
| SP | Martinez, P.Martinez, Pedro # >> | 26 | 1997 | R | 96 | 26 | 26 | 10 | 12 | 3.43 | .278 | 1.14 | 7.8 | 2.5 | 8.2 | 207.1 | 180 | 84 | 79 | 19 | 57 | 189 | 12 | 0 | 0 | 1 | 16 | 3 | 4 | 3.24 |
| SP | Perez, P.Perez, Pascual † >> | 31 | 1988 | R | 83 | 26 | 26 | 13 | 4 | 2.68 | .266 | 1.08 | 6.9 | 2.8 | 4.9 | 204.2 | 157 | 65 | 61 | 11 | 64 | 111 | 5 | 0 | 0 | 2 | 20 | 2 | 7 | 3.58 |
| SP | Strasburg, S.Strasburg, Stephen >> | 24 | 2013 | R | 70 | 25 | 25 | 8 | 12 | 3.70 | .299 | 1.28 | 8.4 | 3.2 | 7.4 | 167.2 | 155 | 76 | 69 | 18 | 59 | 137 | 0 | 0 | 0 | 0 | 15 | 1 | 4 | 3.84 |
| RP | Reardon, J.Reardon, Jeff † >> | 26 | 1981 | R | 94 | 83 | 0 | 13 | 5 | 2.39 | .220 | 0.85 | 4.8 | 2.9 | 5.8 | 94.1 | 50 | 31 | 25 | 6 | 30 | 61 | 0 | 8 | 2 | 0 | 0 | 0 | 1 | 3.49 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 70 | 0 | 3 | 1 | 3.84 | .279 | 1.16 | 8.1 | 2.5 | 8.4 | 58.2 | 52 | 25 | 25 | 6 | 16 | 54 | 0 | 3 | 4 | 0 | 0 | 0 | 1 | 3.31 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 85 | 63 | 0 | 6 | 1 | 3.11 | .296 | 1.25 | 8.5 | 2.9 | 8.2 | 66.2 | 62 | 25 | 23 | 8 | 21 | 60 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 3.76 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 86 | 45 | 0 | 5 | 2 | 1.00 | .221 | 0.83 | 4.0 | 3.5 | 7.3 | 54.0 | 24 | 6 | 6 | 4 | 21 | 44 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 3.56 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 84 | 29 | 0 | 7 | 3 | 3.72 | .297 | 1.27 | 6.5 | 5.0 | 7.3 | 36.1 | 26 | 17 | 15 | 3 | 20 | 29 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 4.14 |
| RP | Rivero, F.Rivero, Felipe >> | 23 | 2015 | L | 54 | 59 | 0 | 3 | 1 | 1.74 | .255 | 0.99 | 6.1 | 2.9 | 5.3 | 46.2 | 31 | 9 | 9 | 0 | 15 | 27 | 0 | 3 | 3 | 0 | 0 | 2 | 3 | 2.93 |