| SP | Quintana, J.Quintana, Jose >> | 28 | 2017 | L | 49 | 26 | 26 | 0 | 3 | 5.23 | .333 | 1.50 | 9.7 | 3.8 | 7.3 | 62.0 | 67 | 47 | 36 | 3 | 26 | 50 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.27 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 93 | 26 | 26 | 1 | 4 | 2.39 | .283 | 1.19 | 5.5 | 5.3 | 9.5 | 71.2 | 43 | 21 | 19 | 7 | 42 | 75 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.94 |
| SP | Darvish, Y.Darvish, Yu >> | 33 | 2020 | R | 77 | 26 | 24 | 1 | 10 | 5.02 | .282 | 1.13 | 7.9 | 2.3 | 7.1 | 66.1 | 58 | 44 | 37 | 12 | 17 | 52 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 4.70 |
| RP | Chafin, A.Chafin, Andrew >> | 31 | 2021 | L | 83 | 76 | 0 | 5 | 3 | 3.66 | .309 | 1.30 | 7.6 | 4.1 | 5.9 | 98.1 | 83 | 46 | 40 | 6 | 45 | 64 | 0 | 1 | 6 | 0 | 0 | 4 | 5 | 3.99 |
| RP | Marmol, C.Marmol, Carlos >> | 28 | 2010 | R | 58 | 75 | 0 | 7 | 3 | 2.58 | .295 | 1.24 | 6.7 | 4.5 | 10.2 | 90.2 | 67 | 29 | 26 | 4 | 45 | 102 | 0 | 4 | 3 | 0 | 0 | 2 | 3 | 2.88 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 33 | 2021 | R | 100 | 78 | 0 | 5 | 1 | 2.05 | .223 | 0.82 | 4.2 | 3.2 | 9.8 | 96.2 | 45 | 23 | 22 | 13 | 34 | 105 | 0 | 7 | 5 | 0 | 0 | 4 | 5 | 3.76 |
| RP | Thielbar, C.Thielbar, Caleb >> | 38 | 2025 | L | 71 | 79 | 0 | 3 | 2 | 2.13 | .235 | 0.91 | 5.9 | 2.4 | 5.4 | 80.1 | 52 | 25 | 19 | 5 | 21 | 48 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 3.44 |
| RP | Merryweather, J.Merryweather, Julian >> | 31 | 2023 | R | 29 | 69 | 0 | 3 | 6 | 3.68 | .329 | 1.47 | 7.6 | 5.6 | 7.4 | 66.0 | 56 | 30 | 27 | 5 | 41 | 54 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 4.21 |
| RP | Norris, D.Norris, Daniel >> | 29 | 2022 | L | 26 | 69 | 0 | 2 | 3 | 3.32 | .284 | 1.17 | 6.5 | 4.1 | 10.0 | 62.1 | 45 | 24 | 23 | 3 | 28 | 69 | 0 | 6 | 2 | 0 | 0 | 1 | 1 | 2.81 |
| RP | Leiter, M.Leiter, Mark >> | 33 | 2024 | R | 45 | 42 | 0 | 2 | 6 | 5.62 | .390 | 1.90 | 11.0 | 6.4 | 11.0 | 41.2 | 50 | 30 | 26 | 4 | 29 | 50 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 4.02 |
| RP | Miller, T.Miller, Tyson >> | 28 | 2024 | R | 79 | 58 | 0 | 15 | 1 | 4.07 | .290 | 1.22 | 7.5 | 3.5 | 6.2 | 86.1 | 72 | 45 | 39 | 16 | 33 | 59 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.23 |