| SP | Jimenez, U.Jimenez, Ubaldo # >> | 26 | 2010 | R | 70 | 15 | 15 | 7 | 5 | 4.31 | .293 | 1.21 | 7.2 | 3.7 | 7.9 | 94.0 | 75 | 45 | 45 | 8 | 39 | 83 | 1 | 0 | 0 | 1 | 8 | 3 | 3 | 3.68 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 55 | 15 | 15 | 4 | 3 | 7.20 | .367 | 1.72 | 10.5 | 5.0 | 8.2 | 65.0 | 76 | 52 | 52 | 17 | 36 | 59 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 6.29 |
| SP | Marquez, G.Marquez, German >> | 23 | 2018 | R | 52 | 15 | 15 | 4 | 1 | 4.15 | .323 | 1.42 | 9.7 | 3.2 | 8.6 | 82.1 | 88 | 48 | 38 | 8 | 29 | 78 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 3.46 |
| SP | Gomber, A.Gomber, Austin >> | 27 | 2021 | L | 50 | 15 | 15 | 6 | 0 | 4.54 | .330 | 1.44 | 8.8 | 4.2 | 7.1 | 79.1 | 77 | 40 | 40 | 14 | 37 | 62 | 0 | 0 | 0 | 0 | 4 | 3 | 2 | 5.25 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 82 | 40 | 0 | 6 | 1 | 2.57 | .276 | 1.11 | 7.4 | 2.6 | 7.7 | 56.0 | 46 | 17 | 16 | 4 | 16 | 48 | 0 | 0 | 0 | 0 | 0 | 2 | 6 | 3.18 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 78 | 37 | 0 | 1 | 4 | 3.54 | .253 | 0.95 | 6.0 | 2.6 | 9.6 | 48.1 | 32 | 22 | 19 | 2 | 14 | 51 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 2.48 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 74 | 19 | 0 | 4 | 0 | 1.65 | .248 | 0.99 | 6.3 | 2.7 | 8.0 | 27.1 | 19 | 6 | 5 | 2 | 8 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.07 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 71 | 14 | 0 | 2 | 1 | 1.72 | .217 | 0.83 | 6.0 | 1.8 | 9.0 | 15.2 | 10 | 3 | 3 | 0 | 3 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 1.60 |