| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 91 | 32 | 32 | 16 | 15 | 3.63 | .268 | 1.06 | 7.9 | 1.6 | 6.5 | 260.0 | 228 | 113 | 105 | 25 | 47 | 189 | 23 | 0 | 0 | 1 | 21 | 10 | 5 | 3.45 |
| SP | Schwellenbach, S.Schwellenbach, Spencer >> | 25 | 2025 | R | 64 | 30 | 30 | 13 | 9 | 4.60 | .304 | 1.29 | 9.4 | 2.2 | 5.3 | 201.2 | 211 | 109 | 103 | 30 | 50 | 119 | 1 | 0 | 0 | 0 | 16 | 3 | 1 | 4.55 |
| SP | Beachy, B.Beachy, Brandon >> | 25 | 2012 | R | 82 | 30 | 30 | 0 | 2 | 3.68 | .294 | 1.23 | 6.7 | 4.4 | 5.7 | 78.1 | 58 | 33 | 32 | 6 | 38 | 49 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 4.28 |
| SP | Teheran, J.Teheran, Julio >> | 27 | 2018 | R | 57 | 29 | 29 | 12 | 7 | 4.01 | .282 | 1.17 | 6.7 | 3.9 | 6.9 | 173.0 | 128 | 81 | 77 | 23 | 75 | 133 | 0 | 0 | 0 | 0 | 14 | 1 | 1 | 4.51 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 76 | 0 | 12 | 6 | 2.26 | .251 | 1.01 | 6.4 | 2.7 | 10.3 | 107.1 | 76 | 28 | 27 | 7 | 32 | 122 | 0 | 3 | 2 | 0 | 0 | 0 | 4 | 2.47 |
| RP | Iglesias, R.Iglesias, Raisel >> | 34 | 2024 | R | 91 | 70 | 0 | 6 | 1 | 2.66 | .274 | 1.13 | 7.1 | 3.2 | 6.4 | 94.2 | 74 | 28 | 28 | 6 | 33 | 67 | 0 | 2 | 2 | 0 | 0 | 0 | 3 | 3.46 |
| RP | Wagner, B.Wagner, Billy >> | 39 | 2010 | L | 85 | 67 | 0 | 7 | 2 | 2.43 | .230 | 0.90 | 5.5 | 2.6 | 9.2 | 92.2 | 56 | 26 | 25 | 6 | 27 | 94 | 0 | 7 | 3 | 0 | 0 | 0 | 1 | 2.68 |
| RP | Northrop, J.Northrop, Jake >> | 30 | 1918 | R | 79 | 66 | 0 | 14 | 7 | 3.41 | .272 | 1.11 | 8.3 | 1.7 | 3.9 | 134.2 | 124 | 53 | 51 | 15 | 26 | 58 | 0 | 10 | 1 | 0 | 0 | 1 | 0 | 4.19 |
| RP | Soriano, R.Soriano, Rafael >> | 28 | 2007 | R | 74 | 46 | 0 | 4 | 3 | 3.68 | .260 | 1.03 | 8.1 | 1.2 | 6.5 | 51.1 | 46 | 26 | 21 | 6 | 7 | 37 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.55 |
| RP | Borbon, P.Borbon, Pedro # >> | 29 | 1996 | L | 55 | 34 | 0 | 5 | 3 | 4.64 | .377 | 1.79 | 11.5 | 4.6 | 6.8 | 33.0 | 42 | 18 | 17 | 4 | 17 | 25 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 4.70 |
| RP | Martinez, C.Martinez, Cristhian >> | 29 | 2011 | R | 45 | 31 | 0 | 2 | 1 | 2.09 | .257 | 0.99 | 5.7 | 3.3 | 5.4 | 47.1 | 30 | 12 | 11 | 6 | 17 | 28 | 0 | 3 | 0 | 0 | 0 | 2 | 1 | 4.68 |