| SP | Skenes, P.Skenes, Paul >> | 23 | 2025 | R | 93 | 28 | 28 | 10 | 9 | 2.49 | .254 | 1.00 | 7.2 | 1.8 | 10.9 | 187.2 | 149 | 54 | 52 | 10 | 38 | 227 | 0 | 0 | 0 | 0 | 21 | 5 | 4 | 1.96 |
| SP | Nelson, R.Nelson, Ryne # >> | 27 | 2025 | R | 80 | 27 | 27 | 4 | 9 | 5.59 | .339 | 1.52 | 10.8 | 2.9 | 7.1 | 124.0 | 149 | 80 | 77 | 17 | 40 | 98 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.22 |
| SP | Taillon, J.Taillon, Jameson >> | 33 | 2025 | R | 75 | 26 | 26 | 9 | 7 | 3.62 | .304 | 1.26 | 8.2 | 3.1 | 7.8 | 154.0 | 141 | 64 | 62 | 21 | 53 | 133 | 0 | 0 | 0 | 0 | 15 | 8 | 1 | 4.23 |
| SP | Littell, Z.Littell, Zack >> | 29 | 2025 | R | 60 | 26 | 26 | 10 | 6 | 4.18 | .330 | 1.44 | 9.9 | 3.1 | 7.8 | 148.2 | 163 | 69 | 69 | 20 | 51 | 129 | 0 | 0 | 0 | 0 | 12 | 6 | 5 | 4.17 |
| SP | Kremer, D.Kremer, Dean # >> | 29 | 2025 | R | 52 | 26 | 26 | 14 | 8 | 4.03 | .301 | 1.27 | 8.8 | 2.7 | 7.7 | 149.2 | 145 | 68 | 67 | 8 | 45 | 127 | 0 | 0 | 0 | 0 | 15 | 3 | 5 | 2.96 |
| RP | Rodríguez, R.Rodríguez, Randy >> | 25 | 2025 | R | 95 | 72 | 0 | 8 | 4 | 3.43 | .288 | 1.17 | 8.1 | 2.5 | 9.5 | 102.1 | 92 | 39 | 39 | 5 | 28 | 108 | 0 | 6 | 5 | 0 | 0 | 4 | 4 | 2.46 |
| RP | Henriquez, R.Henriquez, Ronny >> | 25 | 2025 | R | 78 | 71 | 0 | 6 | 4 | 3.63 | .293 | 1.23 | 7.9 | 3.3 | 9.4 | 96.2 | 84 | 39 | 39 | 7 | 35 | 100 | 0 | 13 | 5 | 0 | 0 | 1 | 0 | 2.99 |
| RP | Slaten, J.Slaten, Justin >> | 27 | 2025 | R | 62 | 68 | 0 | 5 | 4 | 3.05 | .305 | 1.28 | 8.6 | 3.1 | 7.3 | 85.2 | 81 | 30 | 29 | 8 | 29 | 69 | 0 | 7 | 8 | 0 | 0 | 3 | 2 | 3.73 |
| RP | Gaddis, H.Gaddis, Hunter >> | 27 | 2025 | R | 52 | 53 | 0 | 4 | 1 | 3.41 | .266 | 1.07 | 7.3 | 2.3 | 12.9 | 58.0 | 47 | 22 | 22 | 6 | 15 | 83 | 0 | 5 | 1 | 0 | 0 | 1 | 0 | 2.31 |
| RP | Varland, L.Varland, Louie >> | 27 | 2025 | R | 43 | 41 | 0 | 0 | 5 | 4.47 | .325 | 1.42 | 9.4 | 3.5 | 10.4 | 44.1 | 46 | 22 | 22 | 8 | 17 | 51 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 4.27 |
| SP | Wacha, M.Wacha, Michael >> | 33 | 2025 | R | 45 | 23 | 0 | 3 | 2 | 6.11 | .373 | 1.79 | 10.6 | 5.5 | 10.3 | 28.0 | 33 | 19 | 19 | 3 | 17 | 32 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.93 |