| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 25 | 25 | 6 | 10 | 4.54 | .299 | 1.26 | 9.4 | 2.0 | 10.5 | 146.2 | 152 | 76 | 74 | 21 | 33 | 171 | 1 | 0 | 0 | 0 | 14 | 3 | 2 | 3.27 |
| SP | Kelly, M.Kelly, Merrill >> | 36 | 2025 | R | 70 | 25 | 25 | 6 | 9 | 4.59 | .339 | 1.48 | 10.0 | 3.4 | 7.5 | 131.1 | 145 | 72 | 67 | 19 | 50 | 109 | 0 | 0 | 0 | 0 | 9 | 7 | 1 | 4.53 |
| SP | Bibee, T.Bibee, Tanner >> | 26 | 2025 | R | 54 | 24 | 24 | 6 | 9 | 5.41 | .345 | 1.52 | 9.8 | 3.9 | 8.0 | 121.1 | 132 | 73 | 73 | 22 | 53 | 108 | 0 | 0 | 0 | 0 | 10 | 7 | 2 | 5.07 |
| SP | Suarez, R.Suarez, Ranger >> | 29 | 2025 | L | 51 | 24 | 23 | 4 | 15 | 6.61 | .349 | 1.55 | 9.8 | 4.2 | 8.1 | 114.1 | 124 | 86 | 84 | 16 | 53 | 103 | 0 | 0 | 0 | 0 | 6 | 7 | 0 | 4.60 |
| RP | Fisher, B.Fisher, Braydon >> | 24 | 2025 | R | 88 | 75 | 0 | 7 | 6 | 3.38 | .297 | 1.23 | 6.5 | 4.6 | 12.1 | 98.2 | 71 | 37 | 37 | 7 | 50 | 132 | 0 | 1 | 2 | 0 | 0 | 4 | 0 | 2.89 |
| RP | Bender, A.Bender, Anthony >> | 30 | 2025 | R | 77 | 55 | 0 | 1 | 5 | 4.69 | .341 | 1.54 | 9.6 | 4.2 | 9.8 | 71.0 | 76 | 40 | 37 | 8 | 33 | 77 | 0 | 1 | 5 | 0 | 0 | 1 | 1 | 3.73 |
| RP | Santillan, T.Santillan, Tony >> | 28 | 2025 | R | 73 | 47 | 0 | 1 | 1 | 4.66 | .344 | 1.57 | 9.3 | 4.8 | 10.9 | 56.0 | 58 | 29 | 29 | 10 | 30 | 68 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.50 |