| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 22 | 22 | 12 | 8 | 3.46 | .297 | 1.24 | 7.8 | 3.3 | 5.7 | 179.2 | 156 | 72 | 69 | 17 | 66 | 113 | 9 | 0 | 0 | 3 | 12 | 6 | 3 | 4.18 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 81 | 21 | 21 | 7 | 6 | 3.90 | .274 | 1.11 | 6.6 | 3.4 | 9.1 | 131.2 | 96 | 57 | 57 | 16 | 50 | 132 | 0 | 0 | 0 | 0 | 14 | 3 | 6 | 3.79 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 20 | 20 | 5 | 11 | 6.26 | .358 | 1.62 | 10.7 | 4.0 | 4.5 | 141.0 | 167 | 107 | 98 | 19 | 62 | 71 | 5 | 0 | 0 | 0 | 6 | 7 | 5 | 5.21 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 19 | 19 | 5 | 12 | 5.29 | .344 | 1.57 | 10.3 | 3.8 | 6.7 | 143.0 | 164 | 85 | 84 | 19 | 60 | 106 | 4 | 0 | 0 | 2 | 5 | 1 | 2 | 4.52 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 52 | 0 | 2 | 1 | 2.27 | .322 | 1.40 | 7.7 | 5.0 | 9.7 | 67.1 | 57 | 18 | 17 | 4 | 37 | 72 | 0 | 7 | 2 | 0 | 0 | 2 | 4 | 3.37 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 47 | 0 | 2 | 4 | 3.15 | .309 | 1.33 | 6.3 | 5.7 | 9.7 | 54.1 | 38 | 19 | 19 | 5 | 34 | 58 | 0 | 2 | 4 | 0 | 0 | 1 | 1 | 4.00 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 37 | 0 | 5 | 1 | 3.19 | .298 | 1.25 | 5.6 | 5.8 | 8.6 | 42.1 | 26 | 15 | 15 | 2 | 27 | 40 | 0 | 7 | 0 | 0 | 0 | 1 | 1 | 3.71 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 26 | 0 | 4 | 1 | 3.16 | .319 | 1.40 | 7.9 | 5.0 | 7.2 | 25.2 | 22 | 10 | 9 | 1 | 14 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 3.60 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 58 | 1 | 1 | 0 | 0 | 4.05 | .286 | 1.20 | 3.0 | 9.0 | 4.5 | 6.2 | 2 | 3 | 3 | 0 | 6 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.00 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 11 | 0 | 1 | 1 | 3.54 | .330 | 1.43 | 8.6 | 4.5 | 5.0 | 20.1 | 19 | 11 | 8 | 1 | 10 | 11 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 4.20 |