| SP | Kershaw, C.Kershaw, Clayton $$ >> | 28 | 2016 | L | 99 | 22 | 22 | 8 | 8 | 5.27 | .303 | 1.26 | 9.3 | 2.2 | 8.4 | 141.2 | 145 | 86 | 83 | 21 | 34 | 132 | 3 | 0 | 0 | 0 | 10 | 6 | 2 | 3.91 |
| SP | Arrieta, J.Arrieta, Jake $$ >> | 29 | 2015 | R | 92 | 22 | 22 | 5 | 13 | 6.22 | .349 | 1.56 | 10.5 | 3.6 | 8.0 | 131.2 | 153 | 92 | 91 | 25 | 53 | 116 | 1 | 0 | 0 | 0 | 10 | 6 | 2 | 5.06 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 21 | 21 | 7 | 8 | 4.90 | .313 | 1.35 | 9.3 | 2.9 | 4.4 | 108.1 | 111 | 66 | 59 | 15 | 35 | 53 | 0 | 0 | 0 | 0 | 5 | 2 | 2 | 4.85 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 42 | 0 | 2 | 5 | 2.51 | .259 | 1.01 | 6.8 | 2.3 | 8.8 | 46.2 | 35 | 13 | 13 | 2 | 12 | 45 | 0 | 29 | 2 | 0 | 0 | 2 | 1 | 2.52 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 40 | 0 | 2 | 2 | 3.46 | .343 | 1.51 | 7.4 | 6.2 | 8.3 | 39.0 | 32 | 15 | 15 | 5 | 27 | 36 | 0 | 2 | 3 | 0 | 0 | 2 | 0 | 5.05 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 52 | 0 | 3 | 1 | 3.92 | .363 | 1.68 | 10.5 | 4.6 | 6.4 | 62.0 | 72 | 30 | 27 | 8 | 32 | 44 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.90 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 41 | 0 | 3 | 1 | 4.76 | .313 | 1.37 | 8.0 | 4.4 | 9.2 | 45.1 | 40 | 24 | 24 | 10 | 22 | 46 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.31 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 35 | 0 | 0 | 3 | 2.32 | .293 | 1.22 | 6.6 | 4.5 | 6.6 | 42.2 | 31 | 11 | 11 | 4 | 21 | 31 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 4.33 |