| SP | Koufax, S.Koufax, Sandy $$ >> | 30 | 1965 | L | 97 | 12 | 12 | 3 | 6 | 7.96 | .395 | 1.89 | 12.6 | 4.6 | 8.1 | 63.1 | 88 | 61 | 56 | 14 | 32 | 57 | 0 | 0 | 0 | 0 | 2 | 4 | 1 | 5.79 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 12 | 12 | 5 | 6 | 4.14 | .296 | 1.22 | 7.7 | 3.3 | 4.7 | 76.0 | 65 | 37 | 35 | 7 | 28 | 40 | 1 | 0 | 0 | 0 | 6 | 3 | 0 | 4.37 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 12 | 12 | 4 | 5 | 4.66 | .303 | 1.29 | 10.0 | 1.6 | 4.8 | 83.0 | 92 | 46 | 43 | 9 | 15 | 44 | 2 | 0 | 0 | 1 | 5 | 1 | 1 | 3.93 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 11 | 0 | 2 | 1 | 6.85 | .372 | 1.75 | 10.7 | 5.2 | 5.9 | 47.1 | 56 | 39 | 36 | 10 | 27 | 31 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 6.23 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 30 | 0 | 1 | 4 | 3.63 | .298 | 1.25 | 5.9 | 5.5 | 8.6 | 44.2 | 29 | 20 | 18 | 4 | 27 | 42 | 0 | 3 | 4 | 0 | 0 | 1 | 2 | 4.18 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 26 | 0 | 4 | 1 | 1.29 | .239 | 0.94 | 6.4 | 2.1 | 8.5 | 35.0 | 25 | 6 | 5 | 0 | 8 | 33 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 1.80 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 14 | 0 | 0 | 2 | 8.03 | .431 | 2.27 | 15.0 | 6.0 | 7.5 | 12.1 | 20 | 11 | 11 | 1 | 8 | 10 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 11 | 0 | 0 | 0 | 4.02 | .277 | 1.15 | 7.8 | 3.0 | 4.2 | 15.2 | 13 | 7 | 7 | 3 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 5.67 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 12 | 0 | 0 | 0 | 2.87 | .338 | 1.53 | 10.8 | 3.6 | 8.4 | 15.2 | 18 | 7 | 5 | 0 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.33 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 1 | 1 | 1 | 0 | 1.29 | .250 | 1.00 | 6.4 | 2.6 | 6.4 | 7.0 | 5 | 1 | 1 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.43 |