| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 13 | 13 | 7 | 0 | 3.81 | .303 | 1.31 | 8.2 | 3.6 | 9.0 | 85.0 | 77 | 38 | 36 | 9 | 34 | 85 | 2 | 0 | 0 | 1 | 6 | 0 | 0 | 3.58 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 13 | 12 | 3 | 3 | 6.50 | .372 | 1.76 | 12.6 | 3.4 | 6.0 | 63.2 | 88 | 50 | 46 | 11 | 24 | 42 | 1 | 1 | 0 | 0 | 2 | 1 | 2 | 5.13 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 12 | 11 | 4 | 3 | 3.68 | .339 | 1.52 | 9.3 | 4.6 | 8.6 | 63.2 | 65 | 31 | 26 | 4 | 32 | 60 | 0 | 1 | 0 | 0 | 6 | 1 | 2 | 3.49 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 70 | 13 | 11 | 3 | 5 | 7.39 | .364 | 1.70 | 11.7 | 3.5 | 7.6 | 56.0 | 73 | 47 | 46 | 14 | 22 | 47 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 5.80 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 34 | 0 | 4 | 3 | 3.54 | .295 | 1.23 | 7.9 | 3.4 | 8.8 | 40.2 | 35 | 17 | 16 | 8 | 15 | 39 | 0 | 11 | 3 | 0 | 0 | 1 | 2 | 4.85 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 38 | 0 | 4 | 3 | 4.40 | .287 | 1.21 | 7.5 | 3.3 | 8.8 | 43.0 | 36 | 21 | 21 | 11 | 16 | 42 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 5.49 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 38 | 0 | 0 | 0 | 3.55 | .329 | 1.39 | 9.9 | 2.6 | 11.4 | 38.0 | 42 | 17 | 15 | 6 | 11 | 48 | 0 | 1 | 0 | 0 | 0 | 3 | 2 | 3.63 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 38 | 0 | 3 | 4 | 4.66 | .352 | 1.63 | 9.5 | 5.4 | 6.9 | 38.2 | 40 | 23 | 20 | 4 | 23 | 29 | 0 | 0 | 2 | 0 | 0 | 0 | 2 | 4.66 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 30 | 0 | 1 | 2 | 5.15 | .353 | 1.61 | 8.3 | 6.5 | 10.3 | 36.2 | 33 | 21 | 21 | 5 | 26 | 41 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 4.78 |