| SP | deGrom, J.deGrom, Jacob $$ >> | 33 | 2021 | R | 100 | 18 | 18 | 7 | 6 | 4.21 | .287 | 1.20 | 8.1 | 2.8 | 9.2 | 117.2 | 105 | 58 | 55 | 12 | 36 | 120 | 1 | 0 | 0 | 0 | 9 | 1 | 0 | 3.23 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 13 | 13 | 5 | 3 | 4.47 | .314 | 1.36 | 7.7 | 4.7 | 8.2 | 88.2 | 75 | 46 | 44 | 9 | 46 | 80 | 1 | 0 | 0 | 0 | 8 | 1 | 1 | 4.11 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 58 | 15 | 15 | 7 | 6 | 4.78 | .289 | 1.21 | 7.4 | 3.6 | 6.2 | 101.2 | 83 | 55 | 54 | 7 | 40 | 70 | 6 | 0 | 0 | 2 | 8 | 1 | 2 | 3.73 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 34 | 0 | 2 | 2 | 3.23 | .324 | 1.40 | 8.4 | 4.5 | 9.9 | 30.2 | 28 | 14 | 11 | 3 | 15 | 33 | 0 | 13 | 7 | 0 | 0 | 1 | 0 | 3.70 |
| SU | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 26 | 0 | 1 | 3 | 2.86 | .206 | 0.74 | 3.9 | 2.9 | 8.0 | 28.1 | 12 | 9 | 9 | 1 | 9 | 25 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 2.75 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 30 | 0 | 5 | 1 | 2.95 | .297 | 1.22 | 6.9 | 4.3 | 10.7 | 21.1 | 16 | 7 | 7 | 2 | 10 | 25 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.43 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 28 | 0 | 0 | 0 | 2.35 | .207 | 0.78 | 6.3 | 0.8 | 6.3 | 23.0 | 16 | 6 | 6 | 2 | 2 | 16 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.00 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 28 | 0 | 2 | 2 | 5.32 | .327 | 1.45 | 9.0 | 4.1 | 8.6 | 22.0 | 22 | 16 | 13 | 3 | 10 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.23 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 7 | 5 | 1 | 3 | 4.96 | .347 | 1.54 | 9.5 | 4.5 | 5.9 | 52.2 | 55 | 32 | 29 | 4 | 26 | 34 | 1 | 0 | 0 | 0 | 3 | 3 | 1 | 4.37 |