| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 22 | 22 | 7 | 14 | 5.05 | .315 | 1.37 | 9.8 | 2.5 | 9.2 | 146.0 | 159 | 85 | 82 | 17 | 41 | 149 | 3 | 0 | 0 | 0 | 9 | 1 | 0 | 3.34 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 21 | 21 | 6 | 8 | 6.03 | .329 | 1.45 | 10.1 | 2.9 | 10.0 | 112.0 | 126 | 75 | 75 | 15 | 36 | 124 | 0 | 0 | 0 | 0 | 8 | 3 | 6 | 3.57 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 21 | 21 | 7 | 9 | 4.58 | .312 | 1.34 | 9.6 | 2.4 | 7.6 | 141.1 | 151 | 78 | 72 | 16 | 38 | 119 | 7 | 0 | 0 | 0 | 11 | 3 | 1 | 3.66 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 21 | 20 | 5 | 9 | 5.00 | .344 | 1.55 | 9.9 | 4.0 | 4.8 | 135.0 | 149 | 78 | 75 | 13 | 60 | 72 | 2 | 0 | 0 | 1 | 6 | 3 | 4 | 4.59 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 37 | 0 | 3 | 6 | 5.84 | .358 | 1.68 | 10.0 | 5.1 | 10.0 | 37.0 | 41 | 24 | 24 | 5 | 21 | 41 | 0 | 14 | 3 | 0 | 0 | 0 | 1 | 4.24 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 32 | 0 | 2 | 0 | 3.64 | .284 | 1.17 | 9.0 | 1.5 | 7.9 | 42.0 | 42 | 17 | 17 | 3 | 7 | 37 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.74 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 28 | 0 | 1 | 2 | 2.43 | .282 | 1.15 | 5.9 | 4.7 | 11.2 | 29.2 | 19 | 8 | 8 | 3 | 15 | 36 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.52 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 18 | 0 | 0 | 1 | 3.72 | .310 | 1.24 | 6.6 | 4.7 | 11.4 | 19.1 | 14 | 8 | 8 | 2 | 10 | 24 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 3.74 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 18 | 0 | 0 | 0 | 4.15 | .270 | 1.02 | 6.4 | 3.0 | 6.0 | 21.2 | 15 | 10 | 10 | 5 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 6.05 |