| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 30 | 30 | 16 | 10 | 4.18 | .279 | 1.12 | 7.5 | 2.6 | 9.5 | 213.0 | 178 | 107 | 99 | 35 | 61 | 226 | 4 | 0 | 0 | 2 | 12 | 8 | 0 | 3.99 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 29 | 29 | 13 | 10 | 4.48 | .300 | 1.27 | 8.4 | 3.0 | 8.3 | 195.0 | 181 | 101 | 97 | 23 | 66 | 179 | 5 | 0 | 0 | 0 | 14 | 4 | 3 | 3.77 |
| CL | Adams, M.Adams, Mike † $ >> | 31 | 2009 | R | 99 | 62 | 0 | 2 | 4 | 1.83 | .267 | 1.08 | 5.7 | 4.1 | 7.3 | 68.2 | 43 | 18 | 14 | 1 | 31 | 55 | 0 | 35 | 1 | 0 | 0 | 1 | 3 | 2.99 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 62 | 0 | 3 | 5 | 4.20 | .309 | 1.33 | 7.3 | 4.8 | 8.4 | 70.2 | 57 | 34 | 33 | 13 | 37 | 65 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 5.19 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 55 | 0 | 3 | 4 | 4.18 | .322 | 1.39 | 8.0 | 4.6 | 8.0 | 64.2 | 57 | 36 | 30 | 4 | 33 | 57 | 0 | 3 | 1 | 0 | 0 | 2 | 1 | 3.67 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 49 | 0 | 1 | 0 | 3.92 | .290 | 1.21 | 7.8 | 3.2 | 7.8 | 59.2 | 51 | 28 | 26 | 8 | 21 | 51 | 0 | 1 | 1 | 0 | 0 | 1 | 9 | 4.15 |