| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 19 | 19 | 6 | 10 | 4.54 | .310 | 1.33 | 9.4 | 2.6 | 9.0 | 123.0 | 128 | 63 | 62 | 18 | 35 | 123 | 0 | 0 | 0 | 0 | 12 | 3 | 2 | 3.83 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 68 | 18 | 18 | 8 | 8 | 5.77 | .320 | 1.37 | 9.6 | 2.7 | 7.5 | 117.0 | 125 | 76 | 75 | 22 | 35 | 97 | 1 | 0 | 0 | 1 | 7 | 5 | 4 | 4.81 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 18 | 18 | 5 | 8 | 4.90 | .335 | 1.48 | 9.3 | 4.0 | 5.8 | 125.0 | 129 | 77 | 68 | 12 | 56 | 80 | 2 | 0 | 0 | 0 | 10 | 4 | 2 | 4.41 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 44 | 0 | 5 | 2 | 3.60 | .311 | 1.36 | 8.0 | 4.2 | 8.8 | 45.0 | 40 | 27 | 18 | 8 | 21 | 44 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.76 |
| RP | Papelbon, J.Papelbon, Jonathan † >> | 27 | 2007 | R | 92 | 42 | 0 | 2 | 2 | 1.19 | .303 | 1.30 | 7.4 | 4.4 | 11.0 | 45.1 | 37 | 6 | 6 | 2 | 22 | 55 | 0 | 9 | 2 | 0 | 0 | 0 | 0 | 2.60 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 30 | 0 | 4 | 2 | 4.59 | .301 | 1.26 | 9.8 | 1.6 | 7.9 | 33.1 | 36 | 18 | 17 | 6 | 6 | 29 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 4.24 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 25 | 0 | 1 | 0 | 5.25 | .321 | 1.42 | 9.4 | 3.4 | 7.1 | 24.0 | 25 | 15 | 14 | 1 | 9 | 19 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 3.08 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 7 | 0 | 0 | 2 | 2.38 | .333 | 1.50 | 6.5 | 7.4 | 4.9 | 11.1 | 8 | 3 | 3 | 1 | 9 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.55 |