| SP | Koufax, S.Koufax, Sandy † # >> | 30 | 1965 | L | 98 | 19 | 19 | 9 | 8 | 3.86 | .283 | 1.15 | 8.0 | 2.4 | 7.7 | 144.2 | 128 | 66 | 62 | 14 | 38 | 123 | 6 | 0 | 0 | 1 | 10 | 5 | 2 | 3.45 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 18 | 18 | 8 | 6 | 3.99 | .325 | 1.43 | 9.8 | 3.2 | 5.9 | 128.2 | 139 | 68 | 57 | 12 | 45 | 84 | 0 | 0 | 0 | 0 | 8 | 2 | 4 | 4.01 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 18 | 18 | 5 | 6 | 6.32 | .363 | 1.70 | 11.4 | 3.9 | 7.4 | 104.0 | 132 | 77 | 73 | 16 | 45 | 85 | 1 | 0 | 0 | 0 | 7 | 1 | 5 | 4.69 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 18 | 18 | 5 | 8 | 5.43 | .339 | 1.51 | 9.6 | 4.0 | 8.2 | 114.1 | 122 | 71 | 69 | 14 | 51 | 104 | 0 | 0 | 0 | 0 | 6 | 3 | 4 | 4.19 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 18 | 18 | 6 | 4 | 4.45 | .302 | 1.28 | 8.2 | 3.4 | 4.1 | 119.1 | 108 | 61 | 59 | 18 | 45 | 54 | 3 | 0 | 0 | 1 | 9 | 2 | 3 | 5.24 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 50 | 0 | 4 | 3 | 4.04 | .294 | 1.25 | 8.1 | 3.2 | 9.4 | 62.1 | 56 | 32 | 28 | 10 | 22 | 65 | 0 | 5 | 4 | 0 | 0 | 0 | 3 | 4.06 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 20 | 0 | 0 | 3 | 4.50 | .308 | 1.29 | 8.6 | 3.0 | 9.4 | 24.0 | 23 | 12 | 12 | 3 | 8 | 25 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 19 | 0 | 3 | 3 | 3.18 | .284 | 1.19 | 8.2 | 2.9 | 4.1 | 22.2 | 20 | 9 | 8 | 2 | 7 | 10 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.23 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 8 | 0 | 1 | 2 | 5.11 | .351 | 1.62 | 11.3 | 3.8 | 6.8 | 12.1 | 15 | 7 | 7 | 1 | 5 | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.83 |