| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 16 | 16 | 8 | 2 | 2.99 | .253 | 1.00 | 7.0 | 2.0 | 4.4 | 117.1 | 91 | 39 | 39 | 7 | 26 | 57 | 5 | 0 | 0 | 2 | 11 | 2 | 2 | 3.52 |
| SP | Guidry, R.Guidry, Ron # >> | 28 | 1978 | L | 78 | 14 | 14 | 6 | 3 | 5.26 | .330 | 1.47 | 10.2 | 3.0 | 5.0 | 77.0 | 87 | 46 | 45 | 12 | 26 | 43 | 1 | 0 | 0 | 0 | 6 | 1 | 1 | 4.96 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 15 | 14 | 3 | 4 | 3.90 | .291 | 1.22 | 9.3 | 1.7 | 7.6 | 85.1 | 88 | 38 | 37 | 9 | 16 | 72 | 1 | 0 | 0 | 1 | 6 | 1 | 2 | 3.28 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 37 | 0 | 3 | 3 | 2.84 | .249 | 0.99 | 5.7 | 3.3 | 7.0 | 44.1 | 28 | 14 | 14 | 2 | 16 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 3.14 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 25 | 0 | 7 | 0 | 3.43 | .309 | 1.29 | 7.5 | 4.2 | 6.3 | 60.1 | 50 | 24 | 23 | 2 | 28 | 42 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3.58 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 35 | 0 | 0 | 0 | 4.17 | .304 | 1.28 | 8.5 | 3.3 | 10.8 | 36.2 | 34 | 17 | 17 | 6 | 13 | 43 | 0 | 2 | 5 | 0 | 0 | 1 | 2 | 3.94 |
| CL | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 39 | 0 | 4 | 2 | 3.43 | .276 | 1.14 | 7.2 | 3.2 | 9.0 | 39.1 | 31 | 17 | 15 | 3 | 14 | 39 | 0 | 20 | 3 | 0 | 0 | 0 | 0 | 3.08 |
| SP | Liriano, F.Liriano, Francisco # >> | 23 | 2006 | L | 58 | 9 | 7 | 2 | 2 | 7.11 | .375 | 1.77 | 13.1 | 3.2 | 7.5 | 31.2 | 45 | 25 | 25 | 7 | 11 | 26 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 5.42 |