| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 19 | 19 | 7 | 7 | 3.08 | .284 | 1.16 | 7.5 | 3.0 | 5.6 | 131.1 | 109 | 51 | 45 | 10 | 43 | 81 | 0 | 0 | 0 | 0 | 15 | 4 | 0 | 3.83 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 89 | 18 | 18 | 7 | 4 | 3.14 | .250 | 0.98 | 7.0 | 1.8 | 5.3 | 152.0 | 119 | 60 | 53 | 12 | 30 | 89 | 7 | 0 | 0 | 0 | 14 | 3 | 0 | 3.51 |
| SP | Johnson, R.Johnson, Randy † >> | 41 | 2004 | L | 84 | 18 | 18 | 9 | 4 | 2.89 | .266 | 1.05 | 6.8 | 2.7 | 7.1 | 137.0 | 103 | 54 | 44 | 14 | 41 | 108 | 5 | 0 | 0 | 3 | 11 | 5 | 2 | 3.76 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 18 | 18 | 7 | 5 | 3.89 | .292 | 1.21 | 7.0 | 3.9 | 8.1 | 115.2 | 90 | 53 | 50 | 14 | 50 | 104 | 0 | 0 | 0 | 0 | 13 | 3 | 4 | 4.16 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 39 | 0 | 0 | 7 | 3.38 | .285 | 1.20 | 6.6 | 4.3 | 6.0 | 42.2 | 31 | 19 | 16 | 3 | 20 | 28 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 4.02 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 24 | 0 | 2 | 3 | 4.18 | .311 | 1.35 | 9.0 | 3.5 | 7.4 | 23.2 | 23 | 11 | 11 | 2 | 9 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.65 |
| RP | Perkins, G.Perkins, Glen >> | 30 | 2013 | L | 49 | 21 | 0 | 3 | 1 | 4.22 | .418 | 2.06 | 14.4 | 5.4 | 6.3 | 10.2 | 16 | 5 | 5 | 0 | 6 | 7 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 3.70 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 6 | 0 | 0 | 0 | 1.93 | .333 | 1.50 | 6.8 | 9.0 | 15.8 | 4.2 | 3 | 1 | 1 | 1 | 4 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.75 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 6 | 0 | 1 | 1 | 3.00 | .237 | 0.93 | 7.8 | 0.6 | 2.4 | 15.0 | 13 | 5 | 5 | 1 | 1 | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.53 |