| SP | Roark, T.Roark, Tanner >> | 26 | 2013 | R | 82 | 33 | 33 | 1 | 6 | 3.69 | .261 | 1.05 | 7.5 | 2.0 | 5.9 | 92.2 | 77 | 39 | 38 | 14 | 20 | 60 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.36 |
| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 100 | 32 | 32 | 14 | 8 | 3.71 | .295 | 1.25 | 7.7 | 3.5 | 10.6 | 187.0 | 161 | 82 | 77 | 22 | 73 | 221 | 0 | 0 | 0 | 0 | 18 | 1 | 0 | 3.35 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 81 | 32 | 32 | 16 | 9 | 4.36 | .312 | 1.33 | 9.0 | 3.0 | 5.6 | 208.2 | 208 | 109 | 101 | 35 | 70 | 129 | 2 | 0 | 0 | 1 | 17 | 6 | 6 | 5.04 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 24 | 2013 | R | 63 | 32 | 32 | 12 | 11 | 5.37 | .358 | 1.65 | 10.5 | 4.3 | 8.3 | 192.2 | 225 | 122 | 115 | 38 | 92 | 178 | 0 | 0 | 0 | 0 | 13 | 6 | 6 | 5.25 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 79 | 0 | 12 | 4 | 2.91 | .290 | 1.22 | 7.5 | 3.5 | 10.0 | 105.1 | 87 | 37 | 34 | 9 | 41 | 117 | 0 | 5 | 5 | 0 | 0 | 1 | 3 | 3.09 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 86 | 81 | 0 | 10 | 3 | 2.31 | .232 | 0.89 | 5.3 | 2.8 | 5.6 | 140.1 | 82 | 39 | 36 | 9 | 43 | 87 | 0 | 8 | 6 | 0 | 0 | 2 | 1 | 3.56 |
| RP | Peralta, J.Peralta, Joel >> | 34 | 2010 | R | 80 | 63 | 0 | 4 | 7 | 3.54 | .298 | 1.25 | 8.8 | 2.5 | 8.8 | 86.1 | 84 | 37 | 34 | 12 | 24 | 84 | 0 | 8 | 6 | 0 | 0 | 2 | 0 | 3.77 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 79 | 57 | 0 | 3 | 3 | 3.48 | .305 | 1.30 | 7.2 | 4.6 | 8.7 | 64.2 | 51 | 27 | 25 | 8 | 33 | 62 | 0 | 9 | 1 | 0 | 0 | 1 | 3 | 4.28 |
| RP | Kelley, S.Kelley, Shawn >> | 32 | 2016 | R | 62 | 44 | 0 | 2 | 3 | 4.89 | .327 | 1.46 | 9.8 | 3.3 | 10.8 | 46.0 | 50 | 28 | 25 | 7 | 17 | 55 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.70 |
| RP | Weems, J.Weems, Jordan >> | 29 | 2022 | R | 22 | 27 | 0 | 0 | 0 | 4.86 | .333 | 1.47 | 8.5 | 4.9 | 7.6 | 33.1 | 31 | 19 | 18 | 5 | 18 | 28 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 5.00 |
| SP | Martinez, P.Martinez, Pedro † >> | 26 | 1997 | R | 94 | 32 | 0 | 16 | 3 | 3.28 | .297 | 1.24 | 8.0 | 3.2 | 9.5 | 167.1 | 148 | 63 | 61 | 18 | 60 | 176 | 0 | 2 | 0 | 0 | 0 | 4 | 1 | 3.44 |