| SP | Wheeler, Z.Wheeler, Zack † # >> | 35 | 2025 | R | 85 | 20 | 20 | 11 | 3 | 3.63 | .242 | 0.95 | 6.8 | 1.7 | 9.1 | 134.0 | 101 | 59 | 54 | 17 | 26 | 136 | 3 | 0 | 0 | 1 | 13 | 1 | 4 | 3.22 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 75 | 19 | 19 | 8 | 5 | 5.57 | .336 | 1.50 | 10.6 | 3.0 | 6.2 | 114.2 | 134 | 74 | 71 | 20 | 38 | 78 | 1 | 0 | 0 | 0 | 8 | 2 | 0 | 4.96 |
| SP | Schilling, C.Schilling, Curt >> | 26 | 1992 | R | 74 | 19 | 19 | 11 | 3 | 3.58 | .337 | 1.49 | 9.5 | 3.9 | 5.4 | 108.0 | 114 | 53 | 43 | 11 | 47 | 65 | 0 | 0 | 0 | 0 | 6 | 4 | 3 | 4.54 |
| SP | McQuillan, G.McQuillan, George >> | 25 | 1910 | R | 63 | 17 | 17 | 5 | 7 | 6.36 | .354 | 1.62 | 9.8 | 4.8 | 4.7 | 92.0 | 100 | 71 | 65 | 13 | 49 | 48 | 1 | 0 | 0 | 1 | 5 | 2 | 3 | 5.46 |
| RP | Bastardo, A.Bastardo, Antonio >> | 26 | 2011 | L | 78 | 47 | 0 | 4 | 1 | 3.64 | .296 | 1.25 | 6.9 | 4.4 | 8.2 | 59.1 | 45 | 25 | 24 | 6 | 29 | 54 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.02 |
| RP | Strahm, M.Strahm, Matt >> | 32 | 2024 | L | 89 | 45 | 0 | 9 | 1 | 2.01 | .215 | 0.81 | 5.0 | 2.3 | 9.9 | 58.1 | 32 | 14 | 13 | 5 | 15 | 64 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 2.74 |
| RP | Wagner, B.Wagner, Billy >> | 33 | 2004 | L | 82 | 32 | 0 | 3 | 2 | 3.56 | .283 | 1.19 | 6.9 | 3.9 | 11.1 | 30.1 | 23 | 12 | 12 | 3 | 13 | 37 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.13 |
| RP | Valdes, R.Valdes, Raul >> | 34 | 2012 | L | 88 | 18 | 0 | 3 | 0 | 4.00 | .239 | 0.94 | 7.0 | 1.5 | 9.5 | 18.0 | 14 | 9 | 8 | 5 | 3 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 35 | 2023 | R | 59 | 12 | 0 | 0 | 0 | 4.73 | .310 | 1.35 | 5.5 | 6.9 | 9.0 | 13.1 | 8 | 7 | 7 | 1 | 10 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.31 |
| CL | Hoffman, J.Hoffman, Jeff † >> | 30 | 2023 | R | 77 | 31 | 0 | 0 | 1 | 1.88 | .211 | 0.80 | 4.2 | 3.2 | 12.2 | 28.2 | 13 | 6 | 6 | 1 | 10 | 38 | 0 | 27 | 2 | 0 | 0 | 0 | 0 | 1.82 |
| RP | Urbina, U.Urbina, Ugueth >> | 31 | 2005 | R | 48 | 24 | 0 | 2 | 0 | 5.81 | .307 | 1.25 | 8.3 | 3.1 | 9.3 | 26.1 | 24 | 17 | 17 | 6 | 9 | 27 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.19 |