| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 20 | 20 | 6 | 6 | 3.57 | .283 | 1.18 | 6.9 | 3.8 | 8.9 | 133.2 | 102 | 56 | 53 | 11 | 56 | 131 | 3 | 0 | 0 | 1 | 10 | 0 | 2 | 3.37 |
| SP | Martinez, P.Martinez, Pedro >> | 26 | 1997 | R | 90 | 19 | 19 | 8 | 9 | 4.16 | .300 | 1.26 | 7.9 | 3.5 | 7.9 | 151.1 | 133 | 71 | 70 | 14 | 58 | 132 | 8 | 0 | 0 | 0 | 11 | 4 | 3 | 3.69 |
| SP | Youmans, F.Youmans, Floyd † >> | 22 | 1986 | R | 59 | 20 | 19 | 11 | 5 | 3.52 | .318 | 1.39 | 7.2 | 5.3 | 6.9 | 130.1 | 104 | 51 | 51 | 12 | 77 | 100 | 1 | 0 | 0 | 0 | 14 | 1 | 4 | 4.46 |
| SP | Rogers, S.Rogers, Steve >> | 24 | 1973 | R | 65 | 19 | 19 | 7 | 9 | 4.76 | .334 | 1.49 | 9.2 | 4.2 | 4.7 | 138.0 | 141 | 75 | 73 | 16 | 64 | 72 | 6 | 0 | 0 | 1 | 8 | 3 | 6 | 4.92 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 82 | 20 | 19 | 10 | 4 | 3.26 | .285 | 1.17 | 7.7 | 2.9 | 5.5 | 140.2 | 120 | 53 | 51 | 14 | 45 | 85 | 4 | 0 | 0 | 1 | 13 | 3 | 3 | 4.11 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 45 | 0 | 5 | 1 | 3.20 | .289 | 1.19 | 7.4 | 3.5 | 9.7 | 39.1 | 32 | 14 | 14 | 4 | 15 | 42 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.41 |
| RP | Clippard, T.Clippard, Tyler >> | 28 | 2013 | R | 84 | 46 | 0 | 2 | 0 | 0.85 | .235 | 0.92 | 5.1 | 3.2 | 9.6 | 42.1 | 24 | 4 | 4 | 2 | 15 | 45 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 2.55 |
| RP | Reardon, J.Reardon, Jeff >> | 26 | 1981 | R | 87 | 38 | 0 | 1 | 4 | 3.27 | .271 | 1.09 | 7.2 | 2.7 | 5.3 | 44.0 | 35 | 16 | 16 | 3 | 13 | 26 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 3.66 |
| RP | Rivero, F.Rivero, Felipe >> | 23 | 2015 | L | 56 | 34 | 0 | 2 | 2 | 3.47 | .320 | 1.37 | 10.6 | 2.0 | 7.8 | 23.1 | 27 | 11 | 9 | 0 | 5 | 20 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 2.04 |
| RP | Valdez, S.Valdez, Sergio >> | 28 | 1992 | R | 54 | 24 | 0 | 2 | 2 | 2.03 | .266 | 1.09 | 6.2 | 3.8 | 5.5 | 26.2 | 18 | 6 | 6 | 1 | 11 | 16 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.54 |