| SP | Jimenez, U.Jimenez, Ubaldo >> | 26 | 2010 | R | 49 | 33 | 33 | 14 | 12 | 3.98 | .322 | 1.39 | 8.2 | 4.3 | 5.4 | 217.0 | 198 | 97 | 96 | 18 | 103 | 129 | 3 | 0 | 0 | 0 | 23 | 8 | 16 | 4.42 |
| SP | De La Rosa, J.De La Rosa, Jorge >> | 30 | 2011 | L | 36 | 32 | 32 | 0 | 3 | 4.74 | .329 | 1.46 | 8.7 | 4.6 | 7.4 | 79.2 | 76 | 42 | 42 | 12 | 40 | 65 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 4.89 |
| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 35 | 33 | 32 | 6 | 9 | 4.61 | .343 | 1.56 | 9.7 | 4.3 | 6.7 | 160.0 | 172 | 88 | 82 | 20 | 77 | 119 | 0 | 0 | 0 | 0 | 4 | 2 | 1 | 4.62 |
| SP | Stark, D.Stark, Dennis # >> | 28 | 2002 | R | 28 | 31 | 31 | 7 | 8 | 4.39 | .313 | 1.37 | 8.0 | 4.3 | 3.8 | 137.1 | 122 | 68 | 67 | 14 | 66 | 58 | 0 | 0 | 0 | 0 | 2 | 0 | 3 | 4.93 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 66 | 85 | 0 | 11 | 6 | 3.62 | .274 | 1.12 | 7.9 | 2.2 | 8.2 | 121.2 | 106 | 54 | 49 | 11 | 30 | 110 | 0 | 7 | 2 | 0 | 0 | 2 | 0 | 3.16 |
| RP | Buchholz, T.Buchholz, Taylor >> | 27 | 2008 | R | 56 | 53 | 0 | 6 | 3 | 4.28 | .349 | 1.57 | 10.2 | 4.2 | 7.0 | 54.2 | 61 | 31 | 26 | 2 | 25 | 42 | 0 | 9 | 7 | 0 | 0 | 2 | 5 | 3.43 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 69 | 31 | 0 | 1 | 2 | 3.44 | .342 | 1.56 | 8.5 | 5.6 | 8.2 | 34.0 | 32 | 14 | 13 | 0 | 21 | 31 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 3.03 |
| RP | Betancourt, R.Betancourt, Rafael >> | 36 | 2011 | R | 68 | 33 | 0 | 0 | 2 | 1.95 | .279 | 1.16 | 7.5 | 2.9 | 6.3 | 37.0 | 31 | 9 | 8 | 3 | 12 | 26 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.62 |