| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 28 | 28 | 8 | 15 | 4.70 | .319 | 1.39 | 9.8 | 2.7 | 5.1 | 168.1 | 183 | 93 | 88 | 18 | 51 | 96 | 5 | 0 | 0 | 1 | 14 | 3 | 3 | 4.21 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 28 | 27 | 9 | 14 | 5.04 | .325 | 1.41 | 9.3 | 3.5 | 6.9 | 169.2 | 174 | 105 | 95 | 23 | 65 | 130 | 2 | 0 | 0 | 0 | 10 | 6 | 5 | 4.49 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 27 | 27 | 5 | 13 | 6.17 | .374 | 1.71 | 10.3 | 5.1 | 3.4 | 135.2 | 155 | 98 | 93 | 10 | 77 | 51 | 0 | 0 | 0 | 0 | 11 | 11 | 2 | 5.16 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 27 | 27 | 6 | 13 | 5.48 | .355 | 1.61 | 10.8 | 3.6 | 5.9 | 156.0 | 188 | 104 | 95 | 15 | 63 | 103 | 1 | 0 | 0 | 1 | 10 | 7 | 3 | 4.28 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 26 | 25 | 11 | 6 | 4.18 | .322 | 1.40 | 8.3 | 4.3 | 3.7 | 157.1 | 145 | 74 | 73 | 16 | 75 | 64 | 3 | 0 | 0 | 0 | 15 | 4 | 4 | 5.02 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 95 | 0 | 1 | 3 | 3.72 | .284 | 1.18 | 6.4 | 4.3 | 10.2 | 96.2 | 68 | 44 | 40 | 8 | 46 | 109 | 0 | 7 | 1 | 0 | 0 | 1 | 10 | 3.28 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 84 | 0 | 5 | 4 | 3.60 | .320 | 1.37 | 7.1 | 5.2 | 9.1 | 90.0 | 71 | 42 | 36 | 4 | 52 | 91 | 0 | 4 | 3 | 0 | 0 | 4 | 2 | 3.42 |
| RP | Gordon, T.Gordon, Tom # >> | 37 | 2004 | R | 63 | 67 | 0 | 4 | 2 | 5.25 | .333 | 1.47 | 9.3 | 4.0 | 8.0 | 72.0 | 74 | 42 | 42 | 9 | 32 | 64 | 0 | 7 | 2 | 0 | 0 | 2 | 2 | 4.26 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 58 | 0 | 4 | 4 | 4.27 | .297 | 1.22 | 8.9 | 2.2 | 6.9 | 65.1 | 64 | 32 | 31 | 7 | 16 | 50 | 0 | 4 | 2 | 0 | 0 | 3 | 1 | 3.74 |