| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 28 | 28 | 7 | 11 | 4.28 | .295 | 1.21 | 8.1 | 2.8 | 7.1 | 174.2 | 156 | 84 | 83 | 15 | 55 | 138 | 2 | 0 | 0 | 1 | 16 | 8 | 4 | 3.62 |
| SP | Verlander, J.Verlander, Justin † >> | 36 | 2019 | R | 99 | 27 | 27 | 15 | 4 | 2.94 | .254 | 1.00 | 6.8 | 2.3 | 9.1 | 189.2 | 142 | 66 | 62 | 22 | 48 | 192 | 3 | 0 | 0 | 0 | 19 | 4 | 2 | 3.31 |
| RP | Devine, J.Devine, Joey † >> | 25 | 2008 | R | 81 | 45 | 0 | 5 | 1 | 2.32 | .267 | 1.05 | 5.8 | 3.8 | 6.8 | 50.1 | 32 | 15 | 13 | 2 | 21 | 38 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.38 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 16 | 0 | 3 | 2 | 3.82 | .305 | 1.31 | 7.7 | 4.2 | 9.8 | 75.1 | 64 | 32 | 32 | 5 | 35 | 82 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.08 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 56 | 0 | 1 | 9 | 4.61 | .314 | 1.37 | 7.3 | 5.2 | 7.5 | 54.2 | 44 | 28 | 28 | 9 | 31 | 45 | 0 | 32 | 6 | 0 | 0 | 0 | 0 | 5.22 |