| SP | Snell, B.Snell, Blake † >> | 25 | 2018 | L | 81 | 21 | 21 | 10 | 7 | 3.47 | .299 | 1.26 | 7.5 | 3.8 | 8.1 | 124.1 | 104 | 51 | 48 | 10 | 53 | 112 | 0 | 0 | 0 | 0 | 12 | 2 | 10 | 3.57 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 20 | 20 | 6 | 7 | 5.43 | .346 | 1.56 | 10.6 | 3.5 | 5.0 | 107.2 | 126 | 70 | 65 | 15 | 42 | 59 | 2 | 0 | 0 | 0 | 7 | 3 | 2 | 4.98 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 21 | 20 | 8 | 8 | 4.43 | .315 | 1.37 | 8.7 | 3.6 | 4.8 | 130.0 | 126 | 66 | 64 | 18 | 52 | 69 | 4 | 0 | 0 | 2 | 10 | 1 | 2 | 4.96 |
| SP | Bunning, J.Bunning, Jim >> | 35 | 1966 | R | 34 | 21 | 20 | 4 | 9 | 6.84 | .367 | 1.71 | 11.4 | 3.9 | 5.1 | 96.0 | 122 | 83 | 73 | 23 | 42 | 54 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 6.40 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 54 | 0 | 5 | 2 | 3.82 | .298 | 1.25 | 6.9 | 4.4 | 10.7 | 70.2 | 54 | 31 | 30 | 8 | 34 | 83 | 0 | 2 | 0 | 0 | 0 | 2 | 4 | 3.66 |
| SU | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 57 | 0 | 2 | 3 | 4.06 | .332 | 1.49 | 9.8 | 3.7 | 4.9 | 64.1 | 70 | 36 | 29 | 11 | 26 | 35 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 5.36 |
| RP | Orosco, J.Orosco, Jesse >> | 26 | 1983 | L | 24 | 39 | 0 | 2 | 4 | 5.07 | .322 | 1.41 | 9.3 | 3.5 | 5.1 | 60.1 | 62 | 36 | 34 | 6 | 23 | 34 | 0 | 1 | 2 | 0 | 0 | 1 | 1 | 4.37 |