| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 7 | 7 | 3.98 | .279 | 1.14 | 8.3 | 2.0 | 9.3 | 133.1 | 123 | 59 | 59 | 19 | 29 | 137 | 0 | 0 | 0 | 0 | 14 | 3 | 0 | 3.52 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 21 | 21 | 8 | 6 | 4.13 | .323 | 1.41 | 9.7 | 3.1 | 9.3 | 137.1 | 147 | 64 | 63 | 12 | 47 | 141 | 1 | 0 | 0 | 0 | 13 | 3 | 5 | 3.18 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 20 | 20 | 7 | 10 | 3.97 | .288 | 1.21 | 7.8 | 3.1 | 4.8 | 138.1 | 120 | 69 | 61 | 14 | 47 | 73 | 5 | 0 | 0 | 2 | 12 | 1 | 2 | 4.30 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 20 | 20 | 5 | 9 | 6.02 | .352 | 1.57 | 10.3 | 3.9 | 5.9 | 101.2 | 116 | 73 | 68 | 13 | 44 | 66 | 0 | 0 | 0 | 0 | 3 | 6 | 4 | 4.85 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 20 | 20 | 7 | 11 | 6.42 | .362 | 1.64 | 11.7 | 3.2 | 5.2 | 117.2 | 152 | 86 | 84 | 17 | 41 | 67 | 1 | 0 | 0 | 0 | 6 | 7 | 2 | 4.97 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 35 | 0 | 1 | 3 | 2.97 | .259 | 1.05 | 6.3 | 3.3 | 8.3 | 36.1 | 25 | 12 | 12 | 4 | 13 | 33 | 0 | 20 | 3 | 0 | 0 | 0 | 2 | 3.69 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 91 | 49 | 0 | 1 | 4 | 4.26 | .299 | 1.25 | 7.3 | 3.9 | 7.3 | 57.0 | 46 | 31 | 27 | 11 | 25 | 46 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 5.32 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 44 | 0 | 6 | 1 | 3.91 | .296 | 1.26 | 7.7 | 3.8 | 7.9 | 50.2 | 43 | 24 | 22 | 5 | 21 | 44 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.80 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 32 | 0 | 2 | 1 | 6.13 | .328 | 1.44 | 10.6 | 2.5 | 8.5 | 39.2 | 46 | 29 | 27 | 6 | 11 | 37 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.03 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 28 | 0 | 0 | 0 | 1.84 | .235 | 0.92 | 5.6 | 2.8 | 4.3 | 29.1 | 18 | 6 | 6 | 3 | 9 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.31 |