| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 37 | 37 | 18 | 9 | 4.20 | .305 | 1.29 | 8.8 | 2.8 | 9.5 | 242.0 | 236 | 119 | 113 | 31 | 76 | 255 | 2 | 0 | 0 | 0 | 23 | 6 | 1 | 3.57 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 20 | 20 | 6 | 4 | 4.90 | .330 | 1.47 | 10.1 | 3.2 | 4.0 | 108.1 | 121 | 69 | 59 | 15 | 38 | 48 | 1 | 0 | 0 | 1 | 9 | 1 | 3 | 5.00 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 76 | 0 | 16 | 6 | 4.58 | .344 | 1.55 | 11.2 | 2.8 | 8.6 | 98.1 | 122 | 66 | 50 | 12 | 30 | 94 | 0 | 0 | 2 | 0 | 0 | 3 | 1 | 3.68 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 69 | 0 | 3 | 0 | 2.79 | .287 | 1.20 | 6.8 | 4.1 | 8.7 | 93.2 | 70 | 31 | 29 | 3 | 42 | 90 | 0 | 1 | 1 | 0 | 0 | 1 | 6 | 2.87 |
| RP | Soria, J.Soria, Joakim # >> | 24 | 2008 | R | 68 | 62 | 0 | 6 | 1 | 5.24 | .297 | 1.26 | 8.8 | 2.7 | 7.8 | 80.2 | 78 | 49 | 47 | 17 | 24 | 69 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.94 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 67 | 0 | 1 | 2 | 3.32 | .276 | 1.13 | 8.4 | 1.8 | 7.1 | 81.1 | 76 | 31 | 30 | 5 | 16 | 64 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 2.85 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 67 | 0 | 4 | 7 | 4.97 | .345 | 1.58 | 8.3 | 5.9 | 10.1 | 67.0 | 62 | 40 | 37 | 5 | 44 | 75 | 0 | 35 | 7 | 0 | 0 | 0 | 10 | 3.70 |