| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 27 | 27 | 11 | 5 | 3.47 | .300 | 1.26 | 9.6 | 1.7 | 5.5 | 194.1 | 207 | 82 | 75 | 18 | 37 | 119 | 2 | 0 | 0 | 0 | 17 | 6 | 1 | 3.64 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 26 | 26 | 10 | 7 | 3.78 | .300 | 1.27 | 7.7 | 3.7 | 5.1 | 171.1 | 146 | 73 | 72 | 9 | 71 | 96 | 0 | 0 | 0 | 0 | 15 | 3 | 0 | 3.86 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 85 | 26 | 26 | 9 | 9 | 5.28 | .325 | 1.43 | 9.5 | 3.4 | 4.9 | 131.1 | 139 | 83 | 77 | 22 | 49 | 72 | 0 | 0 | 0 | 0 | 8 | 2 | 5 | 5.25 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 25 | 25 | 8 | 14 | 4.52 | .284 | 1.17 | 9.0 | 1.5 | 5.3 | 173.1 | 173 | 90 | 87 | 30 | 29 | 101 | 5 | 0 | 0 | 0 | 11 | 4 | 2 | 4.66 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 24 | 24 | 8 | 11 | 5.26 | .348 | 1.58 | 10.3 | 3.9 | 5.8 | 149.0 | 171 | 100 | 87 | 19 | 65 | 96 | 1 | 0 | 0 | 1 | 9 | 3 | 7 | 4.74 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 53 | 0 | 6 | 4 | 3.20 | .268 | 1.07 | 6.9 | 2.7 | 10.3 | 56.1 | 43 | 20 | 20 | 5 | 17 | 64 | 0 | 30 | 5 | 0 | 0 | 2 | 1 | 2.89 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 52 | 0 | 3 | 5 | 4.30 | .333 | 1.50 | 8.1 | 5.6 | 8.4 | 58.2 | 52 | 32 | 28 | 8 | 36 | 54 | 0 | 2 | 6 | 0 | 0 | 0 | 0 | 4.79 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 63 | 0 | 5 | 1 | 5.12 | .365 | 1.69 | 10.1 | 5.1 | 9.4 | 65.0 | 73 | 39 | 37 | 6 | 37 | 68 | 0 | 4 | 2 | 0 | 0 | 2 | 6 | 3.91 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 58 | 0 | 5 | 1 | 3.59 | .296 | 1.21 | 6.7 | 4.4 | 9.3 | 62.2 | 46 | 29 | 25 | 12 | 30 | 64 | 0 | 3 | 0 | 0 | 0 | 3 | 0 | 5.05 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 31 | 0 | 2 | 0 | 4.64 | .327 | 1.39 | 7.9 | 4.6 | 8.5 | 33.0 | 29 | 19 | 17 | 3 | 17 | 31 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.03 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 25 | 0 | 1 | 0 | 4.21 | .306 | 1.29 | 9.4 | 2.5 | 8.3 | 25.2 | 26 | 12 | 12 | 3 | 7 | 23 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.68 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 30 | 0 | 2 | 1 | 6.40 | .307 | 1.24 | 7.6 | 3.7 | 6.5 | 32.1 | 27 | 26 | 23 | 9 | 13 | 23 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 6.72 |