| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 23 | 23 | 10 | 6 | 3.96 | .325 | 1.39 | 8.9 | 3.6 | 8.6 | 150.0 | 148 | 67 | 66 | 17 | 60 | 144 | 3 | 0 | 0 | 2 | 13 | 9 | 0 | 3.93 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 23 | 23 | 5 | 12 | 5.63 | .348 | 1.59 | 10.2 | 4.1 | 4.6 | 147.0 | 166 | 94 | 92 | 19 | 67 | 75 | 1 | 0 | 0 | 0 | 10 | 2 | 3 | 5.07 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 22 | 22 | 5 | 7 | 5.00 | .341 | 1.56 | 9.3 | 4.7 | 7.7 | 108.0 | 112 | 63 | 60 | 12 | 56 | 92 | 0 | 0 | 0 | 0 | 4 | 0 | 2 | 4.30 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 75 | 0 | 3 | 3 | 3.63 | .279 | 1.15 | 7.7 | 2.6 | 8.7 | 62.0 | 53 | 25 | 25 | 8 | 18 | 60 | 0 | 4 | 4 | 0 | 0 | 1 | 2 | 3.66 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 65 | 0 | 1 | 5 | 5.15 | .313 | 1.30 | 9.9 | 1.8 | 8.3 | 73.1 | 80 | 44 | 42 | 11 | 15 | 67 | 0 | 4 | 3 | 0 | 0 | 5 | 0 | 3.95 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 50 | 0 | 6 | 4 | 4.40 | .324 | 1.43 | 10.2 | 2.8 | 9.3 | 61.1 | 69 | 33 | 30 | 9 | 19 | 63 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 3.79 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 44 | 0 | 2 | 5 | 4.66 | .335 | 1.47 | 8.0 | 5.3 | 9.2 | 46.1 | 41 | 24 | 24 | 6 | 27 | 47 | 0 | 6 | 3 | 0 | 0 | 2 | 2 | 4.54 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 56 | 29 | 0 | 1 | 1 | 2.08 | .262 | 1.04 | 7.1 | 2.4 | 7.7 | 34.2 | 27 | 8 | 8 | 2 | 9 | 29 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 2.94 |
| SP | Chance, D.Chance, Dean >> | 23 | 1964 | R | 53 | 10 | 0 | 1 | 1 | 2.08 | .278 | 1.15 | 7.9 | 3.4 | 6.8 | 8.2 | 7 | 2 | 2 | 1 | 3 | 6 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 4.25 |