| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 26 | 26 | 10 | 14 | 3.88 | .311 | 1.33 | 8.4 | 3.5 | 7.7 | 194.2 | 182 | 90 | 84 | 16 | 76 | 167 | 6 | 0 | 0 | 2 | 16 | 6 | 4 | 3.62 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 24 | 24 | 8 | 12 | 4.40 | .309 | 1.33 | 8.8 | 3.2 | 6.8 | 180.0 | 175 | 94 | 88 | 17 | 64 | 135 | 9 | 0 | 0 | 2 | 9 | 3 | 2 | 3.84 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 24 | 24 | 11 | 12 | 5.05 | .319 | 1.39 | 9.5 | 3.1 | 5.3 | 174.2 | 183 | 105 | 98 | 21 | 60 | 103 | 9 | 0 | 0 | 0 | 8 | 3 | 3 | 4.47 |
| SP | Overall, O.Overall, Orval # >> | 28 | 1909 | R | 57 | 24 | 24 | 8 | 13 | 6.01 | .322 | 1.40 | 8.8 | 3.9 | 5.3 | 151.1 | 147 | 101 | 101 | 24 | 65 | 89 | 2 | 0 | 0 | 1 | 10 | 4 | 4 | 5.26 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 60 | 0 | 2 | 1 | 3.03 | .273 | 1.09 | 7.5 | 2.3 | 8.6 | 86.0 | 72 | 32 | 29 | 4 | 22 | 82 | 0 | 8 | 0 | 0 | 0 | 3 | 4 | 2.57 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 53 | 0 | 3 | 6 | 4.15 | .304 | 1.31 | 9.1 | 2.6 | 6.5 | 65.0 | 66 | 34 | 30 | 9 | 19 | 47 | 0 | 5 | 5 | 0 | 0 | 0 | 1 | 4.23 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 44 | 0 | 1 | 2 | 4.65 | .307 | 1.31 | 9.2 | 2.7 | 5.9 | 50.1 | 51 | 27 | 26 | 8 | 15 | 33 | 0 | 4 | 3 | 0 | 0 | 1 | 2 | 4.72 |