| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 8 | 8 | 3 | 2 | 5.48 | .356 | 1.62 | 8.8 | 5.9 | 7.9 | 47.2 | 46 | 29 | 29 | 0 | 31 | 41 | 0 | 0 | 0 | 0 | 3 | 2 | 3 | 3.36 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 8 | 8 | 2 | 4 | 4.33 | .287 | 1.19 | 8.9 | 2.0 | 4.4 | 60.1 | 59 | 34 | 29 | 13 | 13 | 29 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 5.55 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 8 | 8 | 5 | 2 | 3.38 | .290 | 1.21 | 8.0 | 3.0 | 5.9 | 61.1 | 54 | 27 | 23 | 7 | 20 | 40 | 1 | 0 | 0 | 0 | 6 | 1 | 0 | 4.21 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 8 | 8 | 2 | 5 | 4.74 | .345 | 1.58 | 9.0 | 5.3 | 5.5 | 49.1 | 49 | 33 | 26 | 8 | 29 | 30 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 5.67 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 16 | 0 | 0 | 0 | 1.99 | .284 | 1.19 | 8.2 | 2.9 | 9.8 | 22.2 | 20 | 5 | 5 | 3 | 7 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.55 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 13 | 0 | 2 | 0 | 0.00 | .100 | 0.33 | 1.8 | 1.2 | 7.8 | 15.0 | 3 | 0 | 0 | 0 | 2 | 13 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 1.67 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 76 | 15 | 0 | 2 | 0 | 4.50 | .288 | 1.14 | 6.4 | 3.9 | 6.4 | 14.0 | 10 | 7 | 7 | 0 | 6 | 10 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 3.07 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 9 | 0 | 0 | 0 | 0.79 | .277 | 1.15 | 5.7 | 4.9 | 8.2 | 11.1 | 7 | 1 | 1 | 1 | 6 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.00 |