| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 98 | 24 | 24 | 12 | 6 | 3.14 | .286 | 1.20 | 7.9 | 3.0 | 7.2 | 189.1 | 165 | 72 | 66 | 14 | 62 | 151 | 9 | 0 | 0 | 1 | 16 | 1 | 3 | 3.37 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 84 | 23 | 23 | 8 | 7 | 5.61 | .328 | 1.46 | 10.5 | 2.6 | 5.1 | 114.0 | 133 | 75 | 71 | 16 | 33 | 64 | 0 | 0 | 0 | 0 | 4 | 1 | 3 | 4.60 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 73 | 0 | 3 | 5 | 4.59 | .309 | 1.32 | 8.3 | 3.6 | 8.9 | 80.1 | 74 | 45 | 41 | 14 | 32 | 79 | 0 | 6 | 4 | 0 | 0 | 2 | 0 | 4.58 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 62 | 0 | 4 | 3 | 4.25 | .305 | 1.32 | 8.1 | 3.8 | 9.1 | 72.0 | 65 | 40 | 34 | 11 | 30 | 73 | 0 | 10 | 2 | 0 | 0 | 0 | 0 | 4.21 |
| RP | Hernandez, X.Hernandez, Xavier >> | 28 | 1993 | R | 13 | 30 | 0 | 1 | 1 | 3.69 | .301 | 1.29 | 7.8 | 4.1 | 7.5 | 31.2 | 27 | 14 | 13 | 5 | 14 | 26 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 4.77 |