| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 19 | 19 | 10 | 6 | 4.04 | .304 | 1.29 | 8.5 | 3.1 | 7.9 | 136.0 | 129 | 63 | 61 | 16 | 47 | 119 | 5 | 0 | 0 | 0 | 11 | 2 | 2 | 3.86 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 17 | 17 | 5 | 10 | 4.09 | .300 | 1.28 | 7.4 | 4.2 | 6.1 | 116.2 | 95 | 56 | 53 | 8 | 54 | 79 | 2 | 0 | 0 | 0 | 10 | 1 | 2 | 3.96 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 17 | 17 | 10 | 6 | 3.72 | .284 | 1.16 | 7.6 | 2.9 | 5.3 | 123.1 | 104 | 53 | 51 | 7 | 39 | 72 | 6 | 0 | 0 | 2 | 11 | 4 | 1 | 3.62 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 17 | 17 | 9 | 3 | 3.23 | .301 | 1.28 | 6.9 | 4.6 | 8.1 | 111.1 | 85 | 40 | 40 | 10 | 57 | 100 | 0 | 0 | 0 | 0 | 12 | 2 | 3 | 3.96 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 45 | 0 | 3 | 1 | 2.43 | .225 | 0.86 | 5.2 | 2.6 | 9.4 | 66.2 | 38 | 18 | 18 | 6 | 19 | 69 | 0 | 7 | 1 | 0 | 0 | 1 | 2 | 3.00 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 29 | 0 | 2 | 3 | 1.93 | .240 | 0.95 | 6.8 | 2.0 | 7.0 | 32.2 | 24 | 7 | 7 | 3 | 7 | 25 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 11 | 0 | 0 | 0 | 0.87 | .311 | 1.26 | 6.3 | 5.4 | 9.0 | 10.1 | 7 | 1 | 1 | 0 | 6 | 10 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 3.10 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 6 | 0 | 0 | 0 | 3.18 | .320 | 1.41 | 9.0 | 5.4 | 10.8 | 5.2 | 5 | 2 | 2 | 1 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 12 | 0 | 1 | 0 | 1.88 | .295 | 1.26 | 7.1 | 4.5 | 4.5 | 14.1 | 11 | 3 | 3 | 1 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.43 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 7 | 1 | 4 | 1 | 2.97 | .288 | 1.18 | 8.0 | 2.8 | 4.5 | 36.1 | 32 | 16 | 12 | 2 | 11 | 18 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 3.72 |